Another tick borne disease to guard against. [already in Canada]

Despite its many delights, summer also brings its fair share of pestilence. One, called babesiosis, has only recently been widely recognized as a potentially serious outdoor hazard. According to a very detailed study conducted on Block Island, R.I., it could eventually rival Lyme disease as the most common tick-borne ailment in the United States. But…

A Twist On Lyme: The Challenge of Diagnosing European Lyme Neuroborreliosis

Lyme neuroborreliosis is a tick-borne illness with central and peripheral nervous system manifestations. Clinical features and methods for accurate diagnosis differ across world regions owing to different causative Borrelia species. The importance of these distinctions is highlighted by a 12 year old Canadian girl who acquired Lyme neuroborreliosis in Europe.

Biology and neuropathology of dementia in syphilis and Lyme disease

It has long been known that Treponema pallidum, subspecies pallidum can in late stages of neurosyphilis cause dementia, cortical atrophy, and amyloid deposi- tion. The occurrence of dementia, including subacute presenile dementia, was also reported in association with Lyme disease caused by another spirochete, Borrelia burgdorferi.

The Need for Clinical Judgment in the Diagnosis and Treatment of Lyme Disease

Clinical practice guidelines are increasing in number. Unfortunately, when scientific evidence is uncertain, limited, or evolving, as is often the case, conflict often arises between guideline committees and practicing physicians, who bear the direct responsibility for the care of individual patients.

The Klempner Article

The recent article in the NEJM, “Two Controlled Trials of Antibiotic Treatment in Patients with Persistent Symptoms and a History of Lyme Disease,” by Klempner, et. al., provides some interesting data, but the proper interpretation of this data is of little relevance to both clinical practice and guidelines related to chronic Lyme disease.