How to Remove a Tick
New Podcast: Dr. Theoharis Theoharides, Professor of Immunology at Tufts University School of Medicine in Boston.
Welcome back! Season 2 of the Looking at Lyme podcast starts now. Dr. Theoharides has been on the leading edge... View Article
Categories for Research
Borrelia burgdorferi-Induced Changes in the Class II Self-Immunopeptidome Displayed on HLA-DR Molecules Expressed by Dendritic Cells
September 2020 The MHC class II antigen processing and presentation pathway has evolved to derive short amino acid peptides from... View Article
Phase 4 Block of the Right Bundle Branch Suggesting His-Purkinje System Involvement in Lyme Carditis
[CanLyme Note: As new research unfolds we are discovering that borrelia other than Borrelia burgdorferi (Bb) are pathogenic to humans. Much research... View Article
Evaluation of pathogen specific urinary peptides in tick-borne illnesses
Abstract Mass spectrometry enhanced by nanotechnology can achieve previously unattainable sensitivity for characterizing urinary pathogen-derived peptides. We utilized mass spectrometry... View Article
Canada: Microbiome Composition and Borrelia Detection in Ixodes scapularis Ticks at the Northwestern Edge of Their Range
Abstract Lyme disease-causing Borrelia burgdorferi has been reported in 10–19% of Ixodes ticks from Alberta, Canada, where the tick vector Ixodes scapularis is at the northwestern... View Article
Will this latest Canadian research change the paradigm of testing and lab diagnostics for Lyme disease globally?
Abstract Serological diagnosis of Lyme disease suffers from considerable limitations. Yet, the technique cannot currently be replaced by direct detection... View Article
YebC regulates variable surface antigen VlsE expression and is required for host immune evasion in Borrelia burgdorferi
Oct. 2020 PLOS PATHOGENS Abstract Borrelia burgdorferi, the Lyme disease pathogen causes persistent infection by evading the host immune response.... View Article
New Podcast: Back to the lab with Dr. Melanie Wills from the G. Magnotta Lyme Disease Research Lab at the University of Guelph
“In this episode Sarah talks research, Canadian research that is, with Dr. Melanie Wills. She is the Director of the... View Article
Unintended Consequences: The Perils of Publication and Citation Bias
“The system of scientific communication appears to be more fragile than was once believed.” Decisions made by individuals with particular... View Article
HOW THE INCIDENCE OF AN EM RASH CAN BE INFLATED
[CanLyme Note: In Canada the percentage of people who have a rash with Lyme disease is much lower than stated. This... View Article
Mount Allison University: PPE student Michael Nolan researches ticks and Lyme disease with wildlife management focus
Third-year Philosophy, Politics, and Economics student Michael Nolan spent his summer researching a new area of study for him —... View Article
McMaster University doing research on Lyme disease and pregnancy.
The McMaster Midwifery Research Centre is recruiting people initially to complete an online survey if they have had at least... View Article
Failed Disruption of Tick Feeding, Viability, and Molting after Immunization of Mice and Sheep with Recombinant Ixodes ricinus Salivary Proteins IrSPI and IrLip1
Abstract To identify potential vaccine candidates against Ixodes ricinus and tick-borne pathogen transmission, we have previously sequenced the salivary gland transcriptomes of... View Article
Lyme Disease Patient Outcomes and Experiences; A Retrospective Cohort Study
Abstract Lyme disease is a vector-borne illness caused by Borrelia spp. bacterium spread by ticks to humans and other mammals. Despite being... View Article
Active surveillance of pathogens from ticks collected in New York State suburban parks and schoolyards
First published: 22 July 2020 Abstract Schoolyards and suburban parks are two environments where active tick surveillance may inform... View Article
Motivations and Experiences of Canadians Seeking Treatment for Lyme Disease Outside of the Conventional Canadian Health-Care System
Abstract Objective: We aimed to describe the experiences of Canadians who seek diagnosis and treatment for Lyme disease outside... View Article