New research looks into long Covid and chronic Lyme disease
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New research looks into long Covid and chronic Lyme disease

Researchers at MIT are thinking outside the box with a new long Covid, chronic Lyme disease study. Dr. Mikki Tal is heading the MIT MAESTRO research study which is looking into potential sex differences, predictive diagnostics and immunological, neurological and other mechanisms of chronic illness.  Her team is also investigating immune-pathogen interactions, and the connection…

Medical Gaslighting and Lyme Disease: The Patient Experience
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Medical Gaslighting and Lyme Disease: The Patient Experience

Published December 29, 2023 in Healthcare Authored by Jennifer L. Fagen, Jeremy A. Shelton, Jenna Luché-Thayer Abstract: Even though there are approximately half a million new cases of Lyme disease in the US annually, according to the CDC, it is often undiagnosed or misdiagnosed, which can result in a chronic, multisystemic condition. Lyme disease is…

Research confirms  presence of Borrelia cyst-like structures after antibiotic treatment and uncovers a unique localization of Borrelia species in the brain
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Research confirms  presence of Borrelia cyst-like structures after antibiotic treatment and uncovers a unique localization of Borrelia species in the brain

Research continues to reveal an increasingly complex picture of Lyme disease.

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Whole genome sequencing of human Borrelia burgdorferi isolates reveals linked blocks of accessory genome elements located on plasmids and associated with human dissemination

Abstract Lyme disease is the most common vector-borne disease in North America and Europe. The clinical manifestations of Lyme disease vary based on the genospecies of the infecting Borrelia burgdorferi spirochete, but the microbial genetic elements underlying these associations are not known. Here, we report the whole genome sequence (WGS) and analysis of 299 B. burgdorferi (Bb) isolates derived from…

Children are more than twice as likely to lose their detectable antibodies to Lyme disease bacteria
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Children are more than twice as likely to lose their detectable antibodies to Lyme disease bacteria

Background Lyme borreliosis (LB), caused by Borrelia burgdorferi (Bb), is the most common tick-borne infection in Germany. Antibodies against Bb are prevalent in the general population but information on temporal changes of prevalence and estimates of seroconversion (seroincidence) and seroreversion are lacking, especially for children and adolescents. Aim We aimed at assessing antibodies against Bb and factors associated with seropositivity…

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Female ticks (Ixodes scapularis) infected with Borrelia burgdorferi have increased overwintering survival, with implications for tick population growth

Abstract The tick, Ixodes scapularis, vectors pathogens such as Borrelia burgdorferi, the bacterium that causes Lyme disease. Over the last few decades I. scapularis has expanded its range, introducing a novel health threat into these areas. Warming temperatures appear to be one cause of its range expansion to the north. However, other factors are also involved. We show that…