Borrelia burgdorferi-Induced Changes in the Class II Self-Immunopeptidome Displayed on HLA-DR Molecules Expressed by Dendritic Cells

September 2020 The MHC class II antigen processing and presentation pathway has evolved to derive short amino acid peptides from... View Article

Phase 4 Block of the Right Bundle Branch Suggesting His-Purkinje System Involvement in Lyme Carditis

[CanLyme Note: As new research unfolds we are discovering that borrelia other than Borrelia burgdorferi (Bb) are pathogenic to humans. Much research... View Article

Will this latest Canadian research change the paradigm of testing and lab diagnostics for Lyme disease globally?

Abstract Serological diagnosis of Lyme disease suffers from considerable limitations. Yet, the technique cannot currently be replaced by direct detection... View Article

Lyme Disease Patient Outcomes and Experiences; A Retrospective Cohort Study

Abstract Lyme disease is a vector-borne illness caused by Borrelia spp. bacterium spread by ticks to humans and other mammals. Despite being... View Article

Fatal Lyme carditis presenting as fluctuating high-grade atrioventricular block

RE: Lyme carditis and neuroborreliosis Edward J Cormode [MD, FRCP], Retired paediatrician, Canadian Medical Association The three cases presented in the “Practice “section of... View Article

Motivations and Experiences of Canadians Seeking Treatment for Lyme Disease Outside of the Conventional Canadian Health-Care System

Abstract Objective: We aimed to describe the experiences of Canadians who seek diagnosis and treatment for Lyme disease outside... View Article

A 4-year-old boy with ataxia and aphasia

[CanLyme Note: The rashes shown in this case are dismissed Canada-wide by doctors who are not taught about multiple rashes, and... View Article

Chronic Lyme disease – does it exist?

“Her symptoms started quickly: neck pain, extreme fatigue and intermittent fever and chills. The woman had been healthy until then,... View Article

WSU researchers crack the Lyme disease code

The next time a tick feeds on you, Washington State University researchers hope to make sure persistent arthritis caused by... View Article

Lyme Disease: Diversity of Borrelia Species in California and Mexico Detected Using a Novel Immunoblot Assay

Abstract Background: With more than 300,000 new cases reported each year in the United States of America (USA), Lyme disease... View Article

Lyme Disease Frontiers: Reconciling Borrelia Biology and Clinical Conundrums

Abstract Lyme disease is a complex tick-borne zoonosis that poses an escalating public health threat in several parts of the... View Article

Potential treatment for Lyme disease kills bacteria that may cause lingering symptoms, study finds

March 12, 2020 “For decades, the routine treatment for Lyme disease has been standard antibiotics, which usually kill off the... View Article

The General Symptom Questionnaire-30 (GSQ-30): A Brief Measure of Multi-System Symptom Burden in Lyme Disease

[CanLyme Note: The term post-treatment Lyme disease syndrome (PTLDS) referenced in this article is contentious as it implies treatment has... View Article

Ethnobotanical medicine is effective against the bacterium causing Lyme disease

Neuroscience News February 21, 2020 …” The researchers show that plant extracts from black walnut, cat’s claw, sweet wormwood, Mediterranean... View Article

Disulfiram (Tetraethylthiuram Disulfide) in the Treatment of Lyme Disease and Babesiosis: Report of Experience in Three Cases

Abstract Three patients, each of whom had required intensive open-ended antimicrobial therapy for control of the symptoms of chronic... View Article

Most recent American Psychiatric Association guidelines… check for Lyme disease in evaluation.

[CanLyme Note: The wording indicates locally endemic infectious diseases so that would also include the known co-infections of Lyme and other... View Article

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