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Eradication of Biofilm-Like Microcolony Structures of Borrelia burgdorferi by Daunomycin and Daptomycin but not Mitomycin C in Combination with Doxycycline and Cefuroxime

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Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA https://dx.doi.org/10.3389/fmicb.2016.00062  10 February 2016 Lyme disease, caused by Borrelia burgdorferi, is the most common vector-borne disease in the United States and Europe. While the majority of Lyme disease patients can resolve their symptoms if treated promptly, 10–20% of…

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Drexel University Team Duplicates Dr Alan MacDonald’s Findings of Bacterial Biofilms in Alzheimer’s Plaques

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Feb. 2016   –  Allen et al., J Neuroinfect Dis 2016, 7:1 Dr. Herbert B. Allen and his colleagues at Drexel University, Philadelphia have confirmed the presence of bacterial biofilm substance in autopsy brain tissue from victims of Alzheimer’s disease. The extracellular polysaccharide matrix of the biofilms was detected using periodic acid Schiff (PAS) stain,…

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Mayo Researchers Identify New Borrelia Species that Causes Lyme Disease

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Article sub-heading: Until now, Borrelia burgdorferi was only species believed to cause Lyme disease in North America [Canlyme note: actually, many scientists and patient advocate groups have been trying for decades to point to the obvious – Lyme disease is a borreliosis caused by many strains/species (genotypes), just as influenza is an illness caused by various…

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Looking for Canadian input : Survey on the treatment of Lyme disease outside of Canada [that Canadians have had to seek due to lack of help in Canada].

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Survey on the treatment of Lyme disease outside of Canada We are conducting a survey to estimate the number of Canadians receiving treatment for Lyme disease outside of Canada, and the outcome of that treatment. If you are being treated for Lyme disease outside of Canada, or have previously been treated for Lyme disease outside…

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Overruled: Canadian physician was slapped on the hand for not following IDSA guidelines… appeal decision said he does not have to follow those guidelines.

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This is yet another case of a College of Physicians and Surgeons in Canada, overstepping their right to enforce particular guidelines be followed.  The physician was initially penalized (cautioned) for not following “appropriate” or “recommended” guidelines. The provincial College’s of Physicians and Surgeons across Canada, and federal and provincial health authorities have always stated publicly…

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Ticks that Transmit Lyme Disease Reported in 48.6% of U.S. Counties

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[CanLyme note:  A good take home message from this article linked below is that for government to focus heavily on only known areas where ticks are established, is misguided. Canada is comprised of millions of square kilometers.  Less than one percent of one percent are looked at for Lyme disease in nature. If you have…

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The Need for Clinical Judgment in the Diagnosis and Treatment of Lyme Disease

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Abstract Clinical practice guidelines are increasing in number. Unfortunately, when scientific evidence is uncertain, limited, or evolving, as is often the case, conflict often arises between guideline committees and practicing physicians, who bear the direct responsibility for the care of individual patients. The 2006 Infectious Diseases Society of America guidelines for Lyme disease, which have…

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Ticks parasitizing gallinaceous birds in Canada and first record of Borrelia burgdorferi-infected Ixodes pacificus (Acari: Ixodidae) from California Quail

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Systematic & Applied Acarology 21(1): 1–12 (2016) https://doi.org/10.11158/saa.21.1.1 JOHN D. SCOTT, JOHN F. ANDERSON, LANCE A. DURDEN, MORGAN L. SMITH, JODI M. MANORD & KERRY L. CLARK Abstract In far-western Canada, gallinaceous birds are hosts of hard ticks (Ixodida: Ixodidae) that can carry zoonotic pathogens. In this study, we collected the avian coastal tick, Ixodes…

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Isolation of live Borrelia burgdorferi sensu lato spirochetes from patients with undefined disorders and symptoms not typical for Lyme borreliosis.

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Rudenko, N, et al Clin Microbiol Infect. 2015 Dec 7.  pii: S1198-743X(15)00991-X. doi: 10.1016/j.cmi.2015.11.009. Abstract Lyme borreliosis is a multisystem disorder with diverse spectrum of clinical manifestations, caused by spirochetes of the Borrelia burgdorferi sensu lato complex. It is an infectious disease that can be successfully cured by antibiotic therapy on early stages; however, the possibility…

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Partially fed ticks who then re-attach to a new host can transmit Lyme disease within 24 hours 83% of the time according to study.

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Int J Gen Med. 2015; 8: 1–8. Published online 2014 Dec 19. doi:  10.2147/IJGM.S73791 PMCID: PMC4278789 Lyme borreliosis: a review of data on transmission time after tick attachment “It was also found that partially fed ticks would efficiently re-attach to a new host, and in these new hosts transmission occurred in 83% of cases within…

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United States : CDC Refuses to End Preferential Treatment of IDSA Lyme Guidelines in Response to Citizen Petition Patient advocates cite CDC/IDSA conflicts of interest

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“Fries says, “It’s unacceptable that when a federal government agency is presented with evidence of improprieties, the official response is to confirm the improprieties and indicate they will continue.” Now what will the government of Canada do considering their commitment to open government.  Will they insist Bill C-442 be followed with the good faith intended…

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Distribution and survival of Borrelia miyamotoi in human blood components

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Aaron M. Thorp and Laura Tonnetti Article first published online: 21 DEC 2015 DOI: 10.1111/trf.13398 BACKGROUND Borrelia miyamotoi, the agent of relapsing fever, is a tick-borne spirochete first isolated in Japan in 1994. Since then, the spirochete has been detected in ticks globally, generally in the same vectors as the Lyme disease agent. Human infection has…

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Dr. Judith Miklossy – Video on (Lyme disease) neuroborreliosis relative to Alzheimer’s Disease

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Published on Oct 19, 2014 Judith Miklossy, PhD, held a very interesting presentation at the NorVect Conference 2014. In particular she looked at the connection between Lyme disease and Alzheimer´s disease. Here is an excerpt. All presentations from the NorVect conference can be watched in full length at www.norvect.no Judith was a founding Board member…

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Watch interview of Prof Ying Zhang on Borrelia persisters

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Interview with Prof. Ying Zhang at the NorVect Conference 2015   Published on Sep 29, 2015 Prof Ying Zhang from John Hopkins Bloomberg School of Public Health explains why Lyme disease is so difficult to treat. Having worked with Tuberculosis (TB) for many years, he sees the similarities and differences between these to bacteria. With…

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Belleville, Ontario, Canada: Lyme Disease a concern for Health Unit as more ticks test positive

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Belleville News by Steve Petrick Nov 30th, 2015 Belleville – As a real estate agent in Centre Hastings, Steve Bancroft spends a fair bit of time walking around rural properties. These days, he always makes sure to tuck in his clothing so it’s covering his skin. He’s concerned about ticks and, more specifically, the disease…