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CTV News Atlantic: Mother struggles to get adequate help within the Canadian health care system for her young daughter who has Lyme.

Sadly this lack of help for adequate Lyme disease treatment is a Canada-wide problem due in large part to the very poor information given to physicians and other medical professionals by a private self-proclaimed expert group called the Association of Medical Microbiology and Infectious Diseases Canada.  Provincial and federal governments have ceded control over the…

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UoGuelph’s G Magnotta Lyme Disease Research Lab receives $1.2M for research

May, 2022 “With more ticks and tick bites occurring in Canada year after year, better diagnosis of Lyme disease is the goal of renewed funding from the G. Magnotta Foundation for Vector-Borne Diseases supporting a dedicated Lyme disease research program at the University of Guelph. The G. Magnotta Lyme Disease Research Lab will receive a three-year, $1.2-million grant…

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Hotdocs film festival screens “The Quiet Epidemic” on Lyme disease

Watch this new trailer on Lyme disease being screened this week at the Hotdocs Festival in Toronto. “Lyme Disease was first discovered in 1975, yet there has been very little progress for patients. Meanwhile, ticks are spreading life-threatening diseases around the world. Some people are left without a cure, and many without a diagnosis in…

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The Platelet Fraction is a Novel Reservoir to Detect Lyme Borrelia in Blood

Abstract Serological diagnosis of Lyme disease suffers from considerable limitations. Yet, the technique cannot currently be replaced by direct detection methods, such as bacterial culture or molecular analysis, due to their inadequate sensitivity. The low bacterial burden in vasculature and lack of consensus around blood-based isolation of the causative pathogen, Borrelia burgdorferi, are central to this…

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Capture Sequencing Enables Sensitive Detection of Tick-Borne Agents in Human Blood

March 7, 2022 Abstract Assay sensitivity can be a limiting factor in the use of PCR as a tool for the detection of tick-borne pathogens in blood. We evaluated the performance of Tick-borne disease Capture Sequencing Assay (TBDCapSeq), a capture sequencing assay targeting tick-borne agents, to test 158 whole blood specimens obtained from the Lyme…

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Two-tier testing no better than a flip of a coin: Molecular Microbiological and Immune Characterization of a Cohort of Patients Diagnosed with Early Lyme Disease

ABSTRACT Lyme disease is a tick-borne infection caused by the bacteria Borrelia burgdorferi. Current diagnosis of early Lyme disease relies heavily on clinical criteria, including the presence of an erythema migrans rash. The sensitivity of current gold- standard diagnostic tests relies upon antibody formation, which is typically delayed and thus of limited utility in early…

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An Atypical Presentation of a Severe Case of Anaplasma Phagocytophilum

March 2022 Abstract We report a case of a 79-year-old male presenting to a South Bronx hospital with complaints of fever, shortness of breath, severe thrombocytopenia, hematuria, elevated liver enzymes, and acute renal failure. The patient rapidly progressed to acute hypoxic respiratory failure requiring mechanical ventilation. Treatment was delayed for six days because the tick-borne…

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Neuropathogenicity of non-viable Borrelia burgdorferi ex vivo

[CanLyme Note: We disagree that “appropriate treatment” has been established for borreliosis. Also, this study involved deceased monkeys and is a primary tissue study so it is not representative of what occurs in a living human. There are interesting point made including that dead borrelia remnants can cause havoc.] Abstract Even after appropriate treatment, a proportion…

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Neuropathogenicity of non-viable Borrelia burgdorferi ex vivo

January 2022 Abstract Even after appropriate treatment, a proportion of Lyme disease patients suffer from a constellation of symptoms, collectively called Post-Treatment Lyme Disease Syndrome (PTLDS). Brain PET scan of patients with PTLDS have demonstrated likely glial activation indicating persistent neuroinflammatory processes. It is possible that unresolved bacterial remnants can continue to cause neuroinflammation. In…

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Tick season is upon us

Insects are emerging as the weather warms up and tick season has arrived March 25th, 2022 Now that warmer weather has arrived in the Central Okanagan, check yourself, your children and your pets if you’re out for a walk, bike or hike. Tick season is here, and although Lyme disease is rare in this part…

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Evidence of Manipulated Lyme Disease Diagnostics Presented to Suffolk County, NY Health Commissioner

TruthCures Fri, March 11, 2022, 6:00 AM Nonprofit Group Seeks Remedy for Decades of Inaccurate Lyme Disease Testing GREAT RIVER, N.Y., March 11, 2022 (GLOBE NEWSWIRE) — Nonprofit grassroots organization TruthCures, Inc. held a virtual meeting with Suffolk County, NY Health Commissioner Gregson Pigott, MD, MPH, and multiple other Suffolk County officials Wednesday, March 9,…

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Multidisciplinary Management of Suspected Lyme Borreliosis: Clinical Features of 569 Patients, and Factors Associated with Recovery at 3 and 12 Months, a Prospective Cohort Study

Abstract Introduction. Because patients with a suspicion of Lyme borreliosis (LB) may have experienced difficult care paths, the Tick-Borne Diseases Reference Center (TBD-RC) was started in 2017. The aim of our study was to compare the clinical features of patients according to their final diagnoses, and to determine the factors associated with recovery in the…

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Ticks survive for 27 years in entomologist’s lab

by Binghamton University February 22, 2022 Food is necessary for survival, but an East African species of ticks adapted to survive without feeding for eight years. Not only did they live for a total of 27 years, but they healthily reproduced long after the last male tick died. Julian Shepherd, associate professor of biological sciences, discovered…

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Risk of post-treatment Lyme disease in patients with ideally-treated early Lyme disease: A prospective cohort study.

Abstract Purpose Post-treatment Lyme disease (PTLD) is characterized by patient-reported symptoms after treatment for Borrelia burgdorferi infection. The primary aim of this study was to assess whether participants with a history of Lyme disease (LD) would be more likely to meet criteria for PTLD than those without a history of LD. Methods We conducted a longitudinal, prospective…