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  • Co-infections | Education | For Physicians | Lyme disease | Medical Publications | Miscellaneous | Research

    Capture Sequencing Enables Sensitive Detection of Tick-Borne Agents in Human Blood

    ByCanLyme April 17, 2022

    March 7, 2022 Abstract Assay sensitivity can be a limiting factor in the use of PCR as a tool for the detection of tick-borne pathogens in blood. We evaluated the performance of Tick-borne disease Capture Sequencing Assay (TBDCapSeq), a capture sequencing assay targeting tick-borne agents, to test 158 whole blood specimens obtained from the Lyme…

    Read More Capture Sequencing Enables Sensitive Detection of Tick-Borne Agents in Human BloodContinue

  • Education | For Physicians | Lyme Controversy | Medical Publications | Miscellaneous | Research

    Two-tier testing no better than a flip of a coin: Molecular Microbiological and Immune Characterization of a Cohort of Patients Diagnosed with Early Lyme Disease

    ByCanLyme April 6, 2022April 6, 2022

    ABSTRACT Lyme disease is a tick-borne infection caused by the bacteria Borrelia burgdorferi. Current diagnosis of early Lyme disease relies heavily on clinical criteria, including the presence of an erythema migrans rash. The sensitivity of current gold- standard diagnostic tests relies upon antibody formation, which is typically delayed and thus of limited utility in early…

    Read More Two-tier testing no better than a flip of a coin: Molecular Microbiological and Immune Characterization of a Cohort of Patients Diagnosed with Early Lyme DiseaseContinue

  • Co-infections | Education | For Physicians | Miscellaneous

    An Atypical Presentation of a Severe Case of Anaplasma Phagocytophilum

    ByCanLyme March 29, 2022

    March 2022 Abstract We report a case of a 79-year-old male presenting to a South Bronx hospital with complaints of fever, shortness of breath, severe thrombocytopenia, hematuria, elevated liver enzymes, and acute renal failure. The patient rapidly progressed to acute hypoxic respiratory failure requiring mechanical ventilation. Treatment was delayed for six days because the tick-borne…

    Read More An Atypical Presentation of a Severe Case of Anaplasma PhagocytophilumContinue

  • Education | For Physicians | Miscellaneous | Research

    Neuropathogenicity of non-viable Borrelia burgdorferi ex vivo

    ByCanLyme March 29, 2022July 4, 2025

    [CanLyme Note: We disagree that “appropriate treatment” has been established for borreliosis. Also, this study involved deceased monkeys and is a primary tissue study so it is not representative of what occurs in a living human. There are interesting point made including that dead borrelia remnants can cause havoc.] Abstract Even after appropriate treatment, a proportion…

    Read More Neuropathogenicity of non-viable Borrelia burgdorferi ex vivoContinue

  • Education | For Physicians | Miscellaneous | Research

    Neuropathogenicity of non-viable Borrelia burgdorferi ex vivo

    ByCanLyme March 29, 2022

    January 2022 Abstract Even after appropriate treatment, a proportion of Lyme disease patients suffer from a constellation of symptoms, collectively called Post-Treatment Lyme Disease Syndrome (PTLDS). Brain PET scan of patients with PTLDS have demonstrated likely glial activation indicating persistent neuroinflammatory processes. It is possible that unresolved bacterial remnants can continue to cause neuroinflammation. In…

    Read More Neuropathogenicity of non-viable Borrelia burgdorferi ex vivoContinue

  • Co-infections | Education | For Physicians | Lyme in BC | Media | Miscellaneous | Prevention | Voices on Lyme

    Tick season is upon us

    ByCanLyme March 27, 2022

    Insects are emerging as the weather warms up and tick season has arrived March 25th, 2022 Now that warmer weather has arrived in the Central Okanagan, check yourself, your children and your pets if you’re out for a walk, bike or hike. Tick season is here, and although Lyme disease is rare in this part…

    Read More Tick season is upon usContinue

  • Education | For Physicians | Government | Lyme Controversy | Miscellaneous | Voices on Lyme

    Evidence of Manipulated Lyme Disease Diagnostics Presented to Suffolk County, NY Health Commissioner

    ByCanLyme March 14, 2022

    TruthCures Fri, March 11, 2022, 6:00 AM Nonprofit Group Seeks Remedy for Decades of Inaccurate Lyme Disease Testing GREAT RIVER, N.Y., March 11, 2022 (GLOBE NEWSWIRE) — Nonprofit grassroots organization TruthCures, Inc. held a virtual meeting with Suffolk County, NY Health Commissioner Gregson Pigott, MD, MPH, and multiple other Suffolk County officials Wednesday, March 9,…

    Read More Evidence of Manipulated Lyme Disease Diagnostics Presented to Suffolk County, NY Health CommissionerContinue

  • Education | For Physicians | Lyme Controversy | Miscellaneous | Research

    Multidisciplinary Management of Suspected Lyme Borreliosis: Clinical Features of 569 Patients, and Factors Associated with Recovery at 3 and 12 Months, a Prospective Cohort Study

    ByCanLyme March 13, 2022

    Abstract Introduction. Because patients with a suspicion of Lyme borreliosis (LB) may have experienced difficult care paths, the Tick-Borne Diseases Reference Center (TBD-RC) was started in 2017. The aim of our study was to compare the clinical features of patients according to their final diagnoses, and to determine the factors associated with recovery in the…

    Read More Multidisciplinary Management of Suspected Lyme Borreliosis: Clinical Features of 569 Patients, and Factors Associated with Recovery at 3 and 12 Months, a Prospective Cohort StudyContinue

  • Education | International News | Research

    Ticks survive for 27 years in entomologist’s lab

    ByCanLyme February 24, 2022February 24, 2022

    by Binghamton University February 22, 2022 Food is necessary for survival, but an East African species of ticks adapted to survive without feeding for eight years. Not only did they live for a total of 27 years, but they healthily reproduced long after the last male tick died. Julian Shepherd, associate professor of biological sciences, discovered…

    Read More Ticks survive for 27 years in entomologist’s labContinue

  • Education | For Physicians | Miscellaneous | Research

    Risk of post-treatment Lyme disease in patients with ideally-treated early Lyme disease: A prospective cohort study.

    ByCanLyme February 16, 2022

    Abstract Purpose Post-treatment Lyme disease (PTLD) is characterized by patient-reported symptoms after treatment for Borrelia burgdorferi infection. The primary aim of this study was to assess whether participants with a history of Lyme disease (LD) would be more likely to meet criteria for PTLD than those without a history of LD. Methods We conducted a longitudinal, prospective…

    Read More Risk of post-treatment Lyme disease in patients with ideally-treated early Lyme disease: A prospective cohort study.Continue

  • Education | For Physicians | Lyme disease | Medical Publications | Research

    Estimating the Frequency of Lyme Disease Diagnoses, United States, 2010–2018

    ByCanLyme February 11, 2022

    Abstract By using commercial insurance claims data, we estimated that Lyme disease was diagnosed and treated in ≈476,000 patients in the United States annually during 2010–2018. Our results underscore the need for accurate diagnosis and improved prevention. Lyme disease is caused by Borrelia burgdorferi spirochetes, which are transmitted to humans by certain Ixodes spp. ticks (1). The infection can…

    Read More Estimating the Frequency of Lyme Disease Diagnoses, United States, 2010–2018Continue

  • Education | For Physicians | Lyme disease | Miscellaneous | Research

    Borrelia burgdorferi and Borrelia miyamotoi in Atlantic Canadian wildlife

    ByCanLyme February 11, 2022

    Abstract Borrelia burgdorferi and Borrelia miyamotoi are tick-vectored zoonotic pathogens maintained in wildlife species. Tick populations are establishing in new areas globally in response to climate change and other factors. New Brunswick is a Canadian maritime province at the advancing front of tick population establishment and has seen increasing numbers of ticks carrying B. burgdorferi, and more recently B. miyamotoi. Further, it…

    Read More Borrelia burgdorferi and Borrelia miyamotoi in Atlantic Canadian wildlifeContinue

  • Education | Research

    Lyme-carrying ticks live longer–and could spread farther–thanks to warmer winters

    ByCanLyme January 14, 2022January 14, 2022

    [CanLyme Note: The research referred to in this article was aided by a grant via the Canadian Lyme Disease Foundation’s Venture Grant’s program.] “Experiments suggest infection makes ticks more active in winter PHOENIX–Fearing a case of potentially debilitating Lyme disease, countless hikers postpone their trips to the woods until winter, when the ticks that carry the…

    Read More Lyme-carrying ticks live longer–and could spread farther–thanks to warmer wintersContinue

  • Co-infections | Education | For Physicians | Lyme Controversy | Lyme in Ontario | Miscellaneous | Updates | Voices on Lyme | Your Stories

    Another tragic case of denial and mismanagement of Lyme disease in Ontario using knowingly inaccurate tests to deny diagnosis and treatment.

    ByCanLyme January 12, 2022January 12, 2022

    “From the outside, twenty-eight-year-old Jason Bailey from Ontario seemed to have it made. Born in Brampton, he moved with his mother and younger brother to Orillia after his parents separated. One of two boys raised by a single parent, Jason had your typical Canadian childhood full of outdoor activities and competitive sports. He played AAA…

    Read More Another tragic case of denial and mismanagement of Lyme disease in Ontario using knowingly inaccurate tests to deny diagnosis and treatment.Continue

  • Co-infections | Education | For Physicians | Miscellaneous | Research

    Cat Scratch Disease as a Mimicker of Malignancy

    ByCanLyme January 12, 2022

    Abstract Cat scratch disease (CSD) infrequently mimics malignancy. We reviewed 11 such cases at MD Anderson Cancer Center and an additional 36 reported from the literature. Breast cancer, sarcoma, and lymphoma were the most commonly suspected malignancies. Most patients were young, female, had prior cat exposure, and had no systemic symptoms. Regional lymphadenopathy was the…

    Read More Cat Scratch Disease as a Mimicker of MalignancyContinue

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