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Abstract Changes in cellular metabolism have proven to be important factors in driving cell behavior. It has been shown that cellular metabolism of immune cells changes when exposed to or infected by several pathogens: while this is often an adaptation of the host cells to the infection, sometimes it represents a mechanism through which the…
Abstract The relapsing fever spirochete Borrelia hermsii and the Lyme disease spirochete Borrelia burgdorferi sensu stricto each produces an abundant, orthologous, outer membrane protein, Vtp and OspC, respectively, when transmitted by tick bite. Gene inactivation studies have shown that both proteins are essential for spirochete infectivity when transmitted by their respective tick vectors. Therefore, we transformed a vtp-minus mutant of B….
By Mary Beth Pfeiffer ” Government and medicine have systematically failed to diagnose, treat or prevent a spreading plague of ticks. And they know it. “ For two decades, Lyme disease has had dueling identities. A burgeoning epidemic wrought by ticks. A raging controversy over why patients stay sick – and what to do for…
[CanLyme Note: The term post-treatment Lyme disease syndrome (PTLDS) referenced in this article is contentious as it implies treatment has eradicated the infectious Lyme disease borrelia bacteria. There is an abundance of evidence showing that the bacteria can survive recommended treatment periods. Many people do well with longer term treatment while others do not respond…
Obituary Haefling, Paul M.A. (English), LL.B – Passed away surrounded by his loving wife Catherine of 54 years and family members at the Wellington Terrace Nursing Home in Fergus on Monday, January 13, 2020. Paul Haefling, in his 79th year, was the husband of Catherine (Lipton) Haefling. Predeceased by his parents Jerome and Irene (Sullivan)…
Neuroscience News February 21, 2020 …” The researchers show that plant extracts from black walnut, cat’s claw, sweet wormwood, Mediterranean rockrose, and Chinese skullcap had strong activity against B. burgdorferi, outperforming both tested antibiotics.” Read full article
Abstract The spirochetes Borrelia (Borreliella) burgdorferi and Borrelia hermsii, the etiologic agents of Lyme disease and relapsing fever, respectively, cycle in nature between an arthropod vector and a vertebrate host. They have extraordinarily unusual genomes that are highly segmented and predominantly linear. The genetic analyses of Lyme disease spirochetes have become increasingly more sophisticated, while the age of genetic investigation…
Presenting at a Lyme disease conference held in Bridgewater, NS, in November 2019, it was said that Nova Scotia lacks proper protocols when dealing with the ignored epidemic of Lyme and tick-borne diseases [TBD’s]. We have the highest incidence in Canada conservatively estimated as 454/ 100,000 across the province to as high as 1,826/100,000 in…
[CanLyme Note: In this case the IDSA means Infectious Disease Society of America who are the defendant doctors. The Lyme disease file in Canada is dominated by IDSA, via their Canadian equivalent AMMI, the Association of Medical Microbiology and Infectious Diseases of Canada who are just as devoid of ethical standards who control the highest positions…
Every province in Canada is now endemic for Lyme disease.
In today’s Big Story podcast, it’s a disease we never expected to see with any regularity in Canada, only to realize–perhaps too late–that maybe that was dumb. It’s a mistake to think of Lyme Disease as a rare illness now. Because all the data we have–and we don’t have enough–shows us that it is exploding…
Andrew Rankin (arankin [at] herald [dot] ca) February 11, 2020 SACKVILLE, N.B. – The federal U.S. public health agency has set an example for Canada to follow by acknowledging that Lyme disease could be passed from mother to fetus with serious consequences, says a Mount Allison University expert. “The first step is acknowledging that the…
Produced for the Lunenburg Lyme Association in collaboration with and support from CanLyme (Rob Murray, a CanLyme board member) and the District of Lunenburg, the Province of Nova Scotia, the Town of Bridgewater, the Lunenburg Board of Trade, the East Coast Naturopathic Clinic, South Shore Regional Hospital Auxillary, the Town of Lunenburg, Mahone Bay, the…
Abstract Lyme disease (LD) is caused by the spirochete Borrelia burgdorferi sensu lato (Bbsl). After transmission to humans by ticks, Bbsl spreads to multiple organs, leading to arthritis, carditis, and neuroborreliosis. No effective prophylaxis against human LD prior to tick exposure is currently availa-ble. Thus, a pre-exposure prophylaxis (PrEP) against LD is needed. The establishment of LD…
[CanLyme Note: The title may mislead some to believe they are studying a turkey tick. This is a study of ticks in the country of Turkey.] Abstract This Turkey-based study investigated the presence of various tick-borne microorganisms in a broad-range of host-seeking ticks (n = 1019) that exhibit both hunter and ambusher characteristics. All collected ticks were analyzed…
The Canadian Lyme Disease Foundation is dedicated to promoting research, education, diagnosis and treatment of Lyme and associated diseases.
