Index | Page 99 | CanLyme – Canadian Lyme Disease Foundation

Research
Vascular binding of a pathogen under shear force through mechanistically distinct sequential interactions with host macromolecules
ByCanLyme Team November 17, 2012April 21, 2023
Summary Systemic dissemination of microbial pathogens permits microbes to spread from the initial site of infection to secondary target tissues and is responsible for most mortality due to bacterial infections. Dissemination is a critical stage of disease progression by the Lyme spirochaete, Borrelia burgdorferi. However, many mechanistic features of the process are not yet understood….
Read More Vascular binding of a pathogen under shear force through mechanistically distinct sequential interactions with host macromolecules
Medical Publications | Research
Cotransmission of Divergent Relapsing Fever Spirochetes by Artificially Infected Ornithodoros hermsii
ByCanLyme Team November 17, 2012April 21, 2023
Paul F. Policastro,* Sandra J. Raffel, and Tom G. Schwan Medical Entomology Section, Laboratory of Zoonotic Pathogens, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana 59840 Abstract The soft tick Ornithodoros hermsi, which ranges in specific arboreal zones of western North America, acts as a vector for…
Read More Cotransmission of Divergent Relapsing Fever Spirochetes by Artificially Infected Ornithodoros hermsii
Lyme Controversy | Medical Publications | Miscellaneous
Is multiple sclerosis (MS) a symptom of Lyme disease?
ByCanLyme Team November 12, 2012April 21, 2023
…. and why is there no current ongoing aggressive human pathology being done in Canada specific to looking for Lyme in patients diagnosed with MS considering that Canada has some of the highest per capita rates of MS in the world? Lyme on the Brain (Part 3-A) Lecture Notes of Tom Grier Tomgrier2001 [at] yahoo…
Read More Is multiple sclerosis (MS) a symptom of Lyme disease?
Medical Publications | Research
Bartonella spp. Bacteremia and Rheumatic Symptoms in Patients from Lyme Disease–endemic Region
ByCanLyme Team November 9, 2012April 21, 2023
In Response: We offer the following comments to Beard et al. (1) and Raoult (2) regarding their respective responses to our recent article (3). Before 1990, Bartonella species were not known to infect animals or humans in North America. If not for the AIDS epidemic, the expansion of literature about Bartonella spp. might not have…
Read More Bartonella spp. Bacteremia and Rheumatic Symptoms in Patients from Lyme Disease–endemic Region
Lyme in BC | Medical Publications
Job posting for physicians – Vancouver, BC
ByCanLyme Team November 8, 2012April 21, 2023
Physicians – Complex Chronic Medicine Complex Chronic Diseases Program (CCDP) BC Women’s Hospital and Health Centre UBC Faculty of Medicine Vancouver, BC Part Time (0.05-0.4 FTE, to be determined based on availability) The Complex Chronic Diseases Program (CCDP) is a multidisciplinary program that treats patients with Lyme disease, Fibromyalgia and Myalgic Encephalomyelitis /Chronic Fatigue Syndrome….
Read More Job posting for physicians – Vancouver, BC
Updates | Updates
Santé Canada – Trousses d’analyse pour la maladie de Lyme et limites
ByCanLyme November 7, 2012June 2, 2023
Points clés •Les résultats d’analyses sérologiques sont un supplément au diagnostic clinique de la maladie de Lyme et ne devraient pas constituer la base principale du diagnostic ni des décisions thérapeutiques. •Les trousses d’analyse pour la maladie de Lyme ont des limites de sensibilité et de spécificité. •Les professionnels de la santé devraient connaître ces…
Read More Santé Canada – Trousses d’analyse pour la maladie de Lyme et limites
Updates
Santé Canada – Trousses d’analyse pour la maladie de Lyme et limites
ByCanLyme Team November 7, 2012April 21, 2023
Points clés •Les résultats d’analyses sérologiques sont un supplément au diagnostic clinique de la maladie de Lyme et ne devraient pas constituer la base principale du diagnostic ni des décisions thérapeutiques. •Les trousses d’analyse pour la maladie de Lyme ont des limites de sensibilité et de spécificité. •Les professionnels de la santé devraient connaître ces…
Read More Santé Canada – Trousses d’analyse pour la maladie de Lyme et limites
Medical Publications | Research
Large differences between test strategies for the detection of anti-Borrelia antibodies are revealed by comparing eight ELISAs and five immunoblots.
ByCanLyme Team October 27, 2012April 21, 2023
Ang CW, Notermans DW, Hommes M, Simoons-Smit AM, Herremans T. Source VUMC, Amsterdam, The Netherlands. w [dot] ang [at] vumc [dot] nl Abstract We investigated the influence of assay choice on the results in a two-tier testing algorithm for the detection of anti-Borrelia antibodies. Eighty-nine serum samples from clinically well-defined patients were tested in eight…
Read More Large differences between test strategies for the detection of anti-Borrelia antibodies are revealed by comparing eight ELISAs and five immunoblots.
Medical Publications | Research
Characterization of Biofilm Formation by Borrelia burgdorferi in Vitro
ByCanLyme Team October 27, 2012April 21, 2023
Abstract Borrelia burgdorferi, the causative agent of Lyme disease, has long been known to be capable of forming aggregates and colonies. It was recently demonstrated that Borrelia burgdorferi aggregate formation dramatically changes the in vitro response to hostile environments by this pathogen. In this study, we investigated the hypothesis that these aggregates are indeed…
Read More Characterization of Biofilm Formation by Borrelia burgdorferi in Vitro
International News | Medical Publications | Research
Analysis of an Ordered, Comprehensive STM Mutant Library in Infectious Borrelia burgdorferi: Insights into the Genes Required for Mouse Infectivity
ByCanLyme Team October 26, 2012April 21, 2023
Tao Lin1*, Lihui Gao1, Chuhua Zhang1, Evelyn Odeh1, Mary B. Jacobs3, Loïc Coutte1¤, George Chaconas4, Mario T. Philipp3, Steven J. Norris1,2 ABSTRACT The identification of genes important in the pathogenesis of Lyme disease Borrelia has been hampered by exceedingly low transformation rates in low-passage, infectious organisms. Using the infectious, moderately transformable B. burgdorferi derivative 5A18NP1…
Read More Analysis of an Ordered, Comprehensive STM Mutant Library in Infectious Borrelia burgdorferi: Insights into the Genes Required for Mouse Infectivity
International News | Medical Publications | Miscellaneous | News from CanLyme | Research
Spirochetal ‘debris’ versus persistent infection in chronic Lyme disease: from semantics to science.
ByCanLyme October 22, 2012
Lyme disease is a highly controversial illness that features two opposing camps [1–4]. One camp espouses the viewpoint of the International Lyme and Associated Diseases Society (ILADS) that infection with the Lyme spirochete, Borrelia burgdorferi, can be difficult to detect given the current state of diagnostic tests and that the organism can be hard to…
Read More Spirochetal ‘debris’ versus persistent infection in chronic Lyme disease: from semantics to science.
Government | Government reports & letters | Medical Publications | Research
Lyme disease test kits and limitations
ByCanLyme Team October 22, 2012April 21, 2023
Health Canada : “Lyme disease test kits are class II (IV being the highest risk class) in vitro diagnostic devices. The devices are intended for the detection of antibodies to Borrelia burgdorferi in human serum, plasma or cerebrospinal fluid.1 They are used to provide serologic evidence of B. Burgdorferi exposure.1 Infection can result in dermatologic,…
Read More Lyme disease test kits and limitations
Miscellaneous | Research
Spatial stratification of various Lyme disease spirochetes in a Central European site.
ByCanLyme October 17, 2012
Related Articles Spatial stratification of various Lyme disease spirochetes in a Central European site. FEMS Microbiol Ecol. 2012 Oct 12; Authors: Richter D, Schröder B, Hartmann NK, Matuschka FR Abstract To determine whether the genospecies composition of Lyme disease spirochetes is spatially stratified, we collected questing Ixodes ricinus ticks in neighboring plots where rodents, birds…
Read More Spatial stratification of various Lyme disease spirochetes in a Central European site.
Lyme in Ontario | Media | Medical Publications
Goldhawk Fights Back am740 Zoomers radio – October 17th, 2012- Lyme
ByCanLyme Team October 17, 2012April 21, 2023
Lyme disease was the very hot topic on today’s popular Dale Goldhawk radio show “Goldhawk Fights Back” on Am 740 Zoomer radio in Toronto, Ontario, Canada. (apologies from Jim Wilson who said a Lyme society was first formed in 1889 when in fact it is quite obvious he should of said 1989). Listen to the podcast…
Read More Goldhawk Fights Back am740 Zoomers radio – October 17th, 2012- Lyme
Miscellaneous | Research
A Novel Iron- and Copper-Binding Protein in the Lyme Disease Spirochete.
ByCanLyme October 17, 2012
Related Articles A Novel Iron- and Copper-Binding Protein in the Lyme Disease Spirochete. Mol Microbiol. 2012 Oct 15; Authors: Wang P, Lutton A, Olesik J, Vali H, Li X Abstract Iron and copper are transition metals that can be toxic to cells due to their abilities to react with peroxide to generate hydroxyl radical. Ferritins…
Read More A Novel Iron- and Copper-Binding Protein in the Lyme Disease Spirochete.

News and updates

Announcing the second annual Canadian Tick-Borne Disease Conference

Feeling sick after eating that steak dinner? You could have a rare but potentially severe tick-borne allergy

Elliot Jacobson: Downstream Secondary Illness in Lyme Disease

Why Lyme disease isn’t the only tick-borne infection you need to worry about

Lyme disease and your pregnancy: Why avoiding tick bites could protect your unborn child

Lack of experience no obstacle at this obstacle course

Interventions to manage mold and mycotoxicities

Environmental toxicities: Confounding presentations

Vascular binding of a pathogen under shear force through mechanistically distinct sequential interactions with host macromolecules

Cotransmission of Divergent Relapsing Fever Spirochetes by Artificially Infected Ornithodoros hermsii

Is multiple sclerosis (MS) a symptom of Lyme disease?

Bartonella spp. Bacteremia and Rheumatic Symptoms in Patients from Lyme Disease–endemic Region

Job posting for physicians – Vancouver, BC

Santé Canada – Trousses d’analyse pour la maladie de Lyme et limites

Santé Canada – Trousses d’analyse pour la maladie de Lyme et limites

Large differences between test strategies for the detection of anti-Borrelia antibodies are revealed by comparing eight ELISAs and five immunoblots.

Characterization of Biofilm Formation by Borrelia burgdorferi in Vitro

Analysis of an Ordered, Comprehensive STM Mutant Library in Infectious Borrelia burgdorferi: Insights into the Genes Required for Mouse Infectivity

Spirochetal ‘debris’ versus persistent infection in chronic Lyme disease: from semantics to science.

Lyme disease test kits and limitations

Spatial stratification of various Lyme disease spirochetes in a Central European site.

Goldhawk Fights Back am740 Zoomers radio – October 17th, 2012- Lyme

A Novel Iron- and Copper-Binding Protein in the Lyme Disease Spirochete.

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