Research confirms  presence of Borrelia cyst-like structures after antibiotic treatment and uncovers a unique localization of Borrelia species in the brain
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Research confirms  presence of Borrelia cyst-like structures after antibiotic treatment and uncovers a unique localization of Borrelia species in the brain

Research continues to reveal an increasingly complex picture of Lyme disease.

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Female ticks (Ixodes scapularis) infected with Borrelia burgdorferi have increased overwintering survival, with implications for tick population growth

Abstract The tick, Ixodes scapularis, vectors pathogens such as Borrelia burgdorferi, the bacterium that causes Lyme disease. Over the last few decades I. scapularis has expanded its range, introducing a novel health threat into these areas. Warming temperatures appear to be one cause of its range expansion to the north. However, other factors are also involved. We show that…

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Balsam fir (Abies balsamea) needles and their essential oil kill overwintering ticks (Ixodes scapularis) at cold temperatures

July 29, 2022 Abstract The blacklegged tick, Ixodes scapularis, vectors Borrelia burgdorferi, a bacterium that causes Lyme Disease. Although synthetic pesticides can reduce tick numbers, there are concerns about their potential effects on beneficial insects, such as pollinators. Plant-based pest control agents such as essential oils could provide an alternative because they have low environmental persistency; however,…

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A New Look at Chronic Lyme

By Pamela Weintraub “Many physicians who treat tick-borne diseases now combine conventional medicine with gentler integrative strategies — and more long-term patients are getting well. In the summer of 1997, Jennifer Crystal discovered a red, splotchy rash on her arm. A 19-year-old counselor at a camp in Maine at the time, Crystal had grown up…

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Neuropathogenicity of non-viable Borrelia burgdorferi ex vivo

[CanLyme Note: We disagree that “appropriate treatment” has been established for borreliosis. Also, this study involved deceased monkeys and is a primary tissue study so it is not representative of what occurs in a living human. There are interesting point made including that dead borrelia remnants can cause havoc.] Abstract Even after appropriate treatment, a proportion…

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Multidisciplinary Management of Suspected Lyme Borreliosis: Clinical Features of 569 Patients, and Factors Associated with Recovery at 3 and 12 Months, a Prospective Cohort Study

Abstract Introduction. Because patients with a suspicion of Lyme borreliosis (LB) may have experienced difficult care paths, the Tick-Borne Diseases Reference Center (TBD-RC) was started in 2017. The aim of our study was to compare the clinical features of patients according to their final diagnoses, and to determine the factors associated with recovery in the…

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Estimating the Frequency of Lyme Disease Diagnoses, United States, 2010–2018

Abstract By using commercial insurance claims data, we estimated that Lyme disease was diagnosed and treated in ≈476,000 patients in the United States annually during 2010–2018. Our results underscore the need for accurate diagnosis and improved prevention. Lyme disease is caused by Borrelia burgdorferi spirochetes, which are transmitted to humans by certain Ixodes spp. ticks (1). The infection can…

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New podcast: Exploring Lyme antibiotics with Dr. Kim Lewis

Sarah explores the latest advances in Lyme disease treatment with Dr. Kim Lewis, a researcher, author, University Distinguished Professor and director of Antimicrobial Discovery Center at Northeastern University in Boston. He specializes in molecular science and is currently researching persister cells that lead to tolerance to antibiotics, uncultured bacteria of the environment and the microbiome…

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The Platelet Fraction Is a Novel Reservoir to Detect Lyme Borrelia in Blood

October 29th, 2021 Victoria P Sanderson 1, Iain L Mainprize 1, Lisette Verzijlenberg 1, Cezar M Khursigara 2, Melanie K B Wills 1 Abstract Serological diagnosis of Lyme disease suffers from considerable limitations. Yet, the technique cannot currently be replaced by direct detection methods, such as bacterial culture or molecular analysis, due to their inadequate sensitivity. The low bacterial burden in vasculature and lack…

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New podcast: The quest for better tests

“In today’s podcast, Sarah speaks with Victoria Sanderson about her exciting new research into Lyme disease testing at the University of Guelph. Sanderson is a current medical student and previously completed her Master’s degree at the University of Guelph and became interested in Lyme disease after seeing how much the disease impacted her mother’s life and…

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Better diagnostic testing: antibodies and beyond with Dr. Armin Schwarzbach

Dr. Schwarzbach is a specialist in laboratory medicine and infectious diseases, having worked in the field for over 20 years. He recalls one of his patients who was diagnosed with Multiple Sclerosis and tested positive for a test that was then called a lymphocyte transformation test for Borrelia burgdorferi even though she subsequently tested negative for antibodies…