The Netherlands Journal of Medicine
B.J. Kullberg, A. Berende, J.W.M. van der Meer
Few diseases have aroused more emotional attention in the press and the public than Lyme disease. Discussions have not only focused on the increasing incidence or the choice of appropriate treatment, but also on perceived inadequacy of serological testing and whether or not persisting fatigue, cognitive dysfunction and musculoskeletal pain are ‘real disease’ and related to persistent infection. Large numbers of patients with such symptoms attributed to Lyme disease seek medical opinions, but no consensus on approach or treatment exists.