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Regional Cerebral Blood Flow and Metabolic Rate in Persistent Lyme Encephalopathy

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Campers stand at the edge of the water at sunset watching the stars come out, with the CanLyme logo floating in the foreground.

Arch Gen Psychiatry. 2009;66(5):554-563. doi:10.1001/archgenpsychiatry.2009.29
May 2009, Vol 66, No. 5

Context: There is controversy regarding whether objective neurobiological abnormalities exist after intensive antibiotic treatment for Lyme disease.

Objectives: To determine whether patients with a history of well-characterized Lyme disease and persistent cognitive deficit show abnormalities in global or topographic distributions of regional cerebral blood flow (rCBF) or cerebral metabolic rate (rCMR).

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