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Diastolic Heart Murmur, Nocturnal Back Pain, and Lumbar Rigidity in a 7-Year Girl: An Unusual Manifestation of Lyme Disease in Childhood

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Case Reports in Pediatrics Volume 2012 (2012), Article ID 976961, 3 pagesdoi:10.1155/2012/976961 Case Report Diastolic Heart Murmur, Nocturnal Back Pain, and Lumbar Rigidity in a 7-Year Girl: An Unusual Manifestation of Lyme Disease in Childhood Genn Kameda,1 Silvia Vieker,1 Johannes Hartmann,2 Tim Niehues,3 and Alfred Längler4 1 Department for Child and Adolescent Health, Gemeinschaftskrankenhaus, Gerhard-Kienle…

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Evolving Perspectives on Lyme Borreliosis in Canada

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J.L.H. Sperling1,2, M.J. Middelveen2, D. Klein3, and F.A.H. Sperling*,1 1Department of Biological Sciences, University of Alberta, Edmonton, Canada 2Canadian Lyme Disease Foundation, West Kelowna, British Columbia, Canada 3Department of Family Medicine, University of Alberta, Edmonton, Canada Abstract: With cases now documented in every province, Lyme borreliosis (LB) is emerging as a serious public health risk…

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The Lymphocyte Transformation Test for Borrelia Detects Active Lyme Borreliosis and Verifies Effective Antibiotic Treatment

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Volker von Baehr, Cornelia Doebis, Hans-Dieter Volk, Rüdiger von Baehr Published Date: (05 October, 2012) Borrelia-specific antibodies are not detectable until several weeks after infection and even if they are present, they are no proof of an active infection. Since the sensitivity of culture and PCR for the diagnosis or exclusion of borreliosis is too…

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Chronic or Late Lyme Neuroborreliosis: Present and Future

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Judith Miklossy*, Samuel Donta, Kurt Mueller, Oliver Nolte and George Perry Alzheimer Research Center, Prevention Alzheimer International Foundation, 1921 Martigny-Croix, CP 16, Switzerland This special issue gives a framework of an international effort, to critically and constructively overview the clinical and pathological aspects of Lyme neuroborreliosis and show directions for future practice and research. The…

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A Reappraisal of the U.S. Clinical Trials of Post-Treatment Lyme Disease Syndrome

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Brian A. Fallon, Eva Petkova, John G. Keilp and Carolyn B. Britton Published Date: (05 October, 2012) Four federally funded randomized placebo-controlled treatment trials of post-treatment Lyme syndrome in the United States have been conducted. Most international treatment guidelines summarize these trials as having shown no acute or sustained benefit to repeated antibiotic therapy. The…

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The Psychoimmunology of Lyme/Tick-Borne Diseases and its Association with Neuropsychiatric Symptoms

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Robert C. Bransfield* Abstract: Disease progression of neuropsychiatric symptoms in Lyme/tick-borne diseases can be better understood by greater attention to psychoimmunology. Although there are multiple contributors that provoke and weaken the immune system, infections and persistent infections are significant causes of pathological immune reactions. Immune mediated ef-fects are a significant contributor to the pathophysiological processes…

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Vancouver, BC: 8th Annual LDF International Scientific Conference on Lyme Borreliosis and other Spirochetal and Tick-borne Diseases: with an emphasis on Mechanisms of Lyme Borreliosis Persistency

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1995 International Lyme Disease Conference, Vancouver, BC   Opening… John  Millar, MD – Provincial Health Officer, British Columbia Diane Kindree, BSN – Lyme Borreliosis Society of British Columbia Martina H. Ziska, MD – Lyme Disease Foundation James Katzel, MD Ukiah Valley Medical Center No abstract available James H. Oliver, Jr., PhD Callaway Professor of Biology, Director, Institute…

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Infectious Disease Society of America not ethical, or science based… yet Canada openly endorses them while allowing no victim’s expert input.

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We all have been duped. Infectious Disease [IDSA] Treatment Guidelines Weakened By Paucity of Scientific Evidence Daniel M. Keller, PhD From: Medscape Today November 13, 2009 (Philadelphia, Pennsylvania)— Two separate analyses presented here at the Infectious Diseases Society of America (IDSA) 47th Annual Meeting revealed that most of the society’s treatment guidelines are based on expert…

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Concerns Regarding the Infectious Diseases Society of America Lyme Disease Clinical Practice Guidelines

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Reprints or correspondence: Mr. Jim Wilson, Canadian Lyme Disease Foundation, 2495 Reece Rd., Westbank, BC V4T 1N1, Canada. TO THE EDITOR — The Canadian Lyme Disease Foundation has several concerns with the Infectious Diseases Society of America’s Lyme disease clinical practice guidelines [1]. I shall elaborate. Throughout the guidelines, the erythema migrans rash is referred…

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Highlights on molecular identification of closely related species.

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Authors: Almeida LA, Araujo R Citation: Infect. Genet. Evol. 2012(Sep) Location: IPATIMUP, Institute of Molecular Pathology and Immunology, University of Porto;Rua Dr. Roberto Frias s/n, 4200-465 Porto, Portugal; ICBAS, Instituto de Ciências Biomédicas Abel Salazar, University of Porto, Rua de Jorge Viterbo Ferreira n.° 228, 4050-313 Porto, Portugal. Electronic address: almeida [dot] ligia [dot] mca…

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Virus Disproved as Cause of Chronic Fatigue Syndrome

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The saga of the retrovirus XMRV and chronic fatigue syndrome appears to have ended, now that researchers in a federally funded study said they found no relationship between the retrovirus and the illness. The controversy dates back to 2009, when a paper in the journal Science found a possible connection between chronic fatigue syndrome and…

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Spirochete antigens persist near cartilage after murine Lyme borreliosis therapy.

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https://www.ncbi.nlm.nih.gov/pubmed/22728928 J Clin Invest. 2012 Jul 2;122(7):2652-60. doi: 10.1172/JCI58813. Epub 2012 Jun 25. Bockenstedt LK, Gonzalez DG, Haberman AM, Belperron AA. Source Department of Internal Medicine, Yale University School of Medicine, New Haven, CT, USA. Abstract An enigmatic feature of Lyme disease is the slow resolution of musculoskeletal symptoms that can continue after treatment, with…

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German expert organization of researchers, physicians, and professors publish objections to Infectious Disease Society of America (IDSA) guidelines

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The German organization Deutsche Borreliose Gesellschaft submitted their evidence based objections to the IDSA much maligned Lyme disease guidelines. The Deutsche Borreliose Gesellschaft (German Society of Lyme-Borreliosis) raises objections to the IDSA Lyme Guidelines published in 2006. The fundamental basis for our objections is that the implementation of the IDSA guidelines extends beyond the United…

Lyme retreatment guidance may be flawed
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Lyme retreatment guidance may be flawed

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Deer ticks, Lyme disease, and medical guidance Accepted medical practice discourages antibiotic retreatment in cases where Lyme disease symptoms persist. A new review of studies behind current medical advice says those studies prove nothing.        Photo credit: Centers for Disease Control           A new statistical review calls into question studies that have been  taken as proof that antibiotic retreatment…

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Alzheimer’s disease – a neurospirochetosis. Analysis of the evidence following Koch’s and Hill’s criteria.

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“Borrelia burgdorferi was detected in the brain in 25.3% of AD cases analyzed and was 13 times more frequent in AD compared to controls. Periodontal pathogen Treponemas (T. pectinovorum, T. amylovorum, T. lecithinolyticum, T. maltophilum, T. medium, T. socranskii) and Borrelia burgdorferi were detected using species specific PCR and antibodies. Importantly, co-infection with several spirochetes…