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Borrelia burgdorferi and Borrelia miyamotoi in Atlantic Canadian wildlife

ByCanLyme Team

Abstract Borrelia burgdorferi and Borrelia miyamotoi are tick-vectored zoonotic pathogens maintained in wildlife species. Tick populations are establishing in new areas globally in response to climate change and other factors. New Brunswick is a Canadian maritime province at the advancing front of tick population establishment and has seen increasing numbers of ticks carrying B. burgdorferi, and more recently B. miyamotoi. Further, it…

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Prevalence of Infection and Co-Infection and Presence of Rickettsial Endosymbionts in Ixodes Scapularis (Acari: Ixodidae) in Connecticut, USA.

ByCanLyme Team

Abstract Ixodes scapularis is currently known to transmit 7 pathogens responsible for Lyme disease, anaplasmosis, babesiosis, tick-borne relapsing fever, ehrlichiosis, and Powassan encephalitis. Ixodes scapularis can also be colonized by endosymbiotic bacteria including those in the genus of Rickettsia. We screened 459 I. scapularis ticks submitted to the Connecticut Agricultural Experiment Station Tick Testing Laboratory with the objectives to (1) examine…

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New York State Grants Approval for IGeneX’s Newly Developed Tick-Borne Relapsing Fever (TBRF) ImmunoBlot Tests

ByCanLyme Team

[CanLyme Note: New York State has one of the strictest certification and approval processes in North America for laboratory tests.  Canadian medical authorities have done nothing but lie about, criticize and malign Igenex for many years based upon opinion not science, simply because Canadians were turning to Igenex for better testing. Igenex has helped thousands of…

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Human seroprevalence of Borrelia miyamotoi in Manitoba, Canada, in 2011-2014: a cross-sectional study.

ByCanLyme Team

CMAJ Open. 2017 Sep 6;5(3):E690-E693. doi: 10.9778/cmajo.20170070. Kadkhoda K, et al Abstract BACKGROUND: Hard tick-borne relapsing fever caused by Borrelia miyamotoi has been reported in Russia, the Netherlands, Germany, Japan and the northeastern and upper midwestern United States. We sought to investigate the presence of B. miyamotoi infection in humans in Manitoba, Canada. METHODS: Two hundred…

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Spain has significant risk areas for contracting Lyme disease (borreliosis)

ByCanLyme Team

Molecular identification of Borrelia spirochetes in questing Ixodes ricinus from northwestern Spain Published online December 20th, 2107 Pablo Diaz et al ABSTRACT Background Ixodes ricinus, the predominant tick species in Europe, can transmit the causative agents of important human diseases such as Lyme borreliosis (LB), caused by Borrelia spirochetes. In northern Spain, LB is considered endemic; recently, a significant increase of the…

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DON’T COUNT ON A RELAPSING FEVER TO DIAGNOSE BORRELIA MIYAMOTOI

ByCanLyme Team

You might assume a patient infected with Borrelia miyamotoi, a relapsing fever spirochete, to present with a relapsing fever. However, your assumption would be wrong 48 out of 50 times, according to a case series published in the Annals of Internal Medicine. [1] The authors found that only 2 out of 50 patients infected with…

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Mayo Researchers Identify New Borrelia Species that Causes Lyme Disease

ByTeam

Article sub-heading: Until now, Borrelia burgdorferi was only species believed to cause Lyme disease in North America [Canlyme note: actually, many scientists and patient advocate groups have been trying for decades to point to the obvious – Lyme disease is a borreliosis caused by many strains/species (genotypes), just as influenza is an illness caused by various…

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The Need for Clinical Judgment in the Diagnosis and Treatment of Lyme Disease

ByTeam

Abstract Clinical practice guidelines are increasing in number. Unfortunately, when scientific evidence is uncertain, limited, or evolving, as is often the case, conflict often arises between guideline committees and practicing physicians, who bear the direct responsibility for the care of individual patients. The 2006 Infectious Diseases Society of America guidelines for Lyme disease, which have…

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Identification of Additional Anti-Persister Activity against Borrelia burgdorferi from an FDA Drug Library

ByTeam

Sept, 2015 Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA Abstract   Lyme disease is a leading vector-borne disease in the United States. Although the majority of Lyme patients can be cured with standard 2–4 week antibiotic treatment, 10%–20% of patients continue to suffer from…

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Disease Risk & Landscape Attributes of Tick-Borne Borrelia Pathogens in the San Francisco Bay Area, California

ByTeam

Published: August 19, 2015 – DOI: 10.1371/journal.pone.0134812 Abstract Habitat heterogeneity influences pathogen ecology by affecting vector abundance and the reservoir host communities. We investigated spatial patterns of disease risk for two human pathogens in the Borrelia genus–B. burgdorferi and B. miyamotoi–that are transmitted by the western black-legged tick, Ixodes pacificus. We collected ticks (349 nymphs,…

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Remarkable diversity of tick or mammalian-associated Borreliae in the metropolitan San Francisco Bay Area, California

ByTeam

Natalia Fedorova, Joyce E. Kleinjan, David James, Lucia T. Hui, Hans Peeters, Robert S. Lane Abstract The diversity of Lyme disease (LD) and relapsing fever (RF)-group spirochetes in the metropolitan San Francisco Bay area in northern California is poorly understood. We tested Ixodes pacificus, I. spinipalpis, and small mammals for presence of borreliae in Alameda…

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Human Infections with Borrelia miyamotoi, Japan

ByTeam

[CanLyme note:  Public Health Agency of Canada researchers have reported finding Borrelia miyamotoi in ticks Canada wide. In Canada we have many strains and in North America in general there are many strains within the genus Borrelia that cause infection in humans. To attempt to distinguish what symptoms are from a relapsing fever Borrelia as opposed to a Lyme…

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The prevalence of Borrelia miyamotoi infection, and co-infections with other Borrelia spp. in Ixodes scapularis ticks collected in Canada

ByTeam

Antonia Dibernardo, Tyler Cote, Nicholas H Ogden and L Robbin Lindsay Published: 15 April 2014 Abstract (provisional) Background Blacklegged ticks, Ixodes scapularis are vectors of the tick-borne pathogens Borrelia  burgdorferi, Anaplasma phagocytophilum and Babesia microti. Recently, the I. scapularis-borne   bacterium Borrelia miyamotoi has been linked to human illness in North America. The range of this tick is…

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Tick-borne Pathogens in Northwestern California, USA [ B. miyamotoi is as abundant as its congener B. burgdorferi but is not tested for in humans ]

ByTeam

Daniel J. Salkeld , Stephanie Cinkovich, and Nathan C. Nieto To the Editor: In northwestern California, USA, the western black-legged tick, Ixodes pacificus, is a known vector ofBorrelia burgdorferi, the spirochete that causes Lyme disease.B. miyamotoi, which is more closely related to spirochetes that cause relapsing fever, has also been detected in 2 locations in California (1,2) and has…

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Investigation of Genotypes of Borrelia burgdorferi in Ixodes scapularis Ticks Collected during Surveillance in Canada

ByTeam

Ogden, et al Abstract The genetic diversity of Borrelia burgdorferi sensu stricto, the agent of Lyme disease in North America, has consequences for the performance of serological diagnostic tests and disease severity. To investigate B. burgdorferi diversity in Canada, where Lyme disease is emerging, bacterial DNA in 309 infected adult Ixodes scapularis ticks collected in…