Whole genome sequencing of human Borrelia burgdorferi isolates reveals linked blocks of accessory genome elements located on plasmids and associated with human dissemination

Abstract Lyme disease is the most common vector-borne disease in North America and Europe. The clinical manifestations of Lyme disease vary based on the genospecies of the infecting Borrelia burgdorferi spirochete, but the microbial genetic elements underlying these associations are not known. Here, we report the whole genome sequence (WGS) and analysis of 299 B. burgdorferi (Bb) isolates derived from…

Windsor, Canada: Parents credit antibiotic for autistic child’s ‘monumental’ improvements

[CanLyme note: Many parents with autistic children who have also received treatment for a Lyme disease infection report similar amazing results from antibiotic treatment leading to hypotheses that some autism may be an infectious disease origin.] Brian Cross, Windsor Star, published February 12th, 2016 A five-year-old boy with autism who has never really communicated, has suddenly started answering back…