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Complete Remission in Paralytic Late Tick-Borne Neurological Disease Comprising Mixed Involvement of Borrelia, Babesia, Anaplasma, and Bartonella: Use of Long-Term Treatments with Antibiotics and Antiparasitics in a Series of 10 Cases

Abstract This study aimed to demonstrate that severe neurological motor deficits in the context of late tick-borne disease with mixed microorganism involvement are eligible for long-term combined antibiotic/antiparasitic treatments. The inclusion criteria were: 1. neurological limb paralysis with a disability score >4 according to the EDSS Kurtzke disability scale; 2. serological tests pointing to an…

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Molecular Detection of Anaplasma phagocytophilum, Babesia odocoilei, Babesia species and Borrelia burgdorferi Sensu Lato in Songbirds

Abstract The blacklegged tick, Ixodes scapularis, is known to carry various tick-borne zoonotic pathogens with the potential to cause debilitating human and animal diseases. Juvenile I. scapularis parasitize songbirds and, perhaps, these avifauna are competent hosts of common microbial pathogens. We extracted brachial venous blood from 18 groundforaging passerine birds that were parasitized by I….

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Evaluation of pathogen specific urinary peptides in tick-borne illnesses

Abstract Mass spectrometry enhanced by nanotechnology can achieve previously unattainable sensitivity for characterizing urinary pathogen-derived peptides. We utilized mass spectrometry enhanced by affinity hydrogel particles (analytical sensitivity = 2.5 pg/mL) to study tick pathogen-specific proteins shed in the urine of patients with (1) erythema migrans rash and acute symptoms, (2) post treatment Lyme disease syndrome (PTLDS), and (3)…

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CBC News: Yarmouth horse owner spreads word about little-known tick-borne disease

Nov. 5th, 2019 A Yarmouth, N.S., horse owner wants others to know about anaplasma, a tick-borne disease that her horse, Sloane, contracted before Halloween. “If you see swollen legs on your horse, it means something, do something,” said Sarah LeBlanc, Sloane’s owner. Anaplasma causes serious fevers, loss of appetite and swollen and painful limbs. If a fever is left…

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Global TV, Winnipeg, Canada: Winnipeggers cautioned to watch out for ticks [Lyme on increase]

May 24th, 2016 WINNIPEG — A Winnipeg mom is warning people to be on the lookout for black legged ticks inside the city. Marnie Le Page’s daughter Brooke contracted Lyme disease in December, 2014. “She came home with a headache, a severe head ache and a fever, went to bed, and since that day she’s never…

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Survey of Ixodes pacificus Ticks in California Reveals a Diversity of Microorganisms and a Novel and Widespread Anaplasmataceae Species.

Sept. 16, 2015 DOI: 10.1371/journal.pone.0135828 Eshoo MW, Carolan HE, Massire C, Chou DM, Crowder CD, Rounds MA, et al. Abstract Ixodes pacificus ticks can harbor a wide range of human and animal pathogens. To survey the prevalence of tick-borne known and putative pathogens, we tested 982 individual adult and nymphal I. pacificus ticks collected throughout…