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Evaluation of pathogen specific urinary peptides in tick-borne illnesses

Abstract Mass spectrometry enhanced by nanotechnology can achieve previously unattainable sensitivity for characterizing urinary pathogen-derived peptides. We utilized mass spectrometry enhanced by affinity hydrogel particles (analytical sensitivity = 2.5 pg/mL) to study tick pathogen-specific proteins shed in the urine of patients with (1) erythema migrans rash and acute symptoms, (2) post treatment Lyme disease syndrome (PTLDS), and (3)…

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Death of Hampton man with rare tick-borne virus probed

[CanLyme Note: Powassan virus was first reported in Powassan, Ontario, Canada in 1958.  (McLean DM, McQueen EJ, Petite HE, MacPherson LW, Scholten TH, Ronald K. Powassan virus: field investigations in Northern Ontario, 1959 to 1961. Can Med Assoc J (1962) 86(21):971–4.) 2017… “The prevalence of POWV in endemic areas may be much higher than originally believed. Some asymptomatic people in these…

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Study cites Powassan link to long-term Lyme symptoms

August 14th, 2016 By Cynthia McCormick Scientists at a Wisconsin laboratory say they suspect persistent cases of Lyme disease may be complicated by the potentially deadly Powassan virus that’s been making headlines in recent years, including on Cape Cod. Developing a better understanding of the frequency of the Powassan virus in humans could help doctors…

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Exclusive: Encephalitis virus found in local ticks

First there was Lyme disease. Then came two malaria-like infectious diseases, babesiosis and anaplasmosis. Now a new study indicates that an unexpectedly high percentage of black-legged ticks in the mid-Hudson Valley also carry a virus that can cause swelling of the brain and, in some cases, death. The study, published today in the journal Parasites…