Tag Archives: neuroborreliosis

MicroRNA and mRNA Transcriptome Profiling in Primary Human Astrocytes Infected with Borrelia burgdorferi.

Abstract   Lyme disease is caused by infection with the bacterium Borrelia burgdorferi (Bb), which is transmitted to humans by deer ticks. The infection manifests usually as a rash and minor systemic symptoms; however, the bacteria can spread to other tissues, causing joint pain, carditis, and neurological symptoms. Lyme neuroborreliosis presents itself in several ways, such as Bell’s palsy, meningitis, Continues →

Teenager with stroke-like symptoms had Lyme: Acute Lyme Neuroborreliosis With Transient Hemiparesis and Aphasia

DOI: http://dx.doi.org/10.1016/j.annemergmed.2015.01.011 February 25, 2015 Nervous system involvement in Lyme disease often mimics other conditions and thus represents a diagnostic challenge, especially in an emergency department setting. We report a case of a female teenager presenting with sudden-onset aphasia and transient right-sided faciobrachial hemiplegia, along with headache and agitation. Ischemia, vasculitis, or another structural lesion was excluded by brain imaging. Continues →

Chronic neuroborreliosis by B. garinii: an unusual case presenting with epilepsy and multifocal brain MRI lesions

Giovanni Matera, et al  NEW MICROBIOLOGICA, 37, 393-397, 2014 Late/chronic Lyme neuroborreliosis (LNB) represents a challenging entity whose diagnosis requires a combination of clinical and laboratory findings, surrounded by much controversy.  Here we describe a patient who had a peculiar form of late LNB with CNS lesions shown by magnetic resonance imaging (MRI), and epileptic seizures, etiologically diagnosed by conventional Continues →

The Neuropsychiatric Assessment of Lyme Disease

Objective: A structured clinical interview is proposed to assist in the overall clinical assessment when late state Lyme disease is suspected. Method:  From a combination of clinical experience, journal review, and discussion with colleagues, a structured interview was developed. Information from patients with late stage neuropsychiatric Lyme disease (NPLD) was entered into a database to serve as a reference point Continues →

(case report) Lyme Neuroborreliosis Manifesting as an Intracranial Mass Lesion

Neurosurgery Issue: Volume 30(5), May 1992, p 769-773 Copyright: Copyright (C) by the Congress of Neurological Surgeons Publication Type: [Case Report] ISSN: 0148-396X Accession: 00006123-199205000-00021 Keywords: Lyme disease, Stereotaxis [Case Report] Lyme Neuroborreliosis Manifesting as an Intracranial Mass Lesion Murray, Rhett M.D.; Morawetz, Richard M.D.; Kepes, John M.D.; El Gammal, Taher M.D.; LeDoux, Mark M.D. Author Information Department of Surgery, Continues →

Acute polyradiculoneuritis syndrome: clinical observations and differential diagnosis [important to rule out Lyme disease].

Authors: Supanc V, Stojić I, Vargek-Solter V, Breitenfeld T, Roje-Bedeković M and Demarin V Citation: Acta Clin Croat 2012(Jun); 51(2): 195-9. Location: University Department of Neurology, Sestre milosrdnice University Hospital Center, Zagreb, Croatia. visnjasupanc@inet.hr Guillain-Barré syndrome (GBS) and neuroborreliosis may clinically manifest with symptoms related to acute polyradiculoneuritis. The aim and purpose of this study was analysis of clinical picture Continues →

Persisting atypical and cystic forms of Borrelia burgdorferi and local inflammation in Lyme neuroborreliosis

Abstract Background The long latent stage seen in syphilis, followed by chronic central nervous system infection and inflammation, can be explained by the persistence of atypical cystic and granular forms of Treponema pallidum. We investigated whether a similar situation may occur in Lyme neuroborreliosis. Method Atypical forms of Borrelia burgdorferi spirochetes were induced exposing cultures of Borrelia burgdorferi (strains B31 Continues →