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Chronic persistent late Lyme disease not a new phenomenon

Chronic Lyme borreliosis in the laboratory mouse. Am J Pathol. 1993 Sep; 143(3): 959–971 Abstract C3H/HeJ mice were inoculated intraperitoneally with 10(7) uncloned Borrelia burgdorferi at 4 weeks of age and examined on days 30, 90, 180, and 360. Spirochetes were isolated from multiple tissues at all intervals. Joint and heart disease were present in…

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The Global Search for Education: More Research – Ticks, Lyme disease, Monica Embers discusses animal model research.

 C.M. Rubin The take home for me from Katie Couric’s recent report on Lyme disease is that there are still too many unanswered questions. We need more research to understand Lyme, which affects 300,000 victims each year because we don’t have answers. We do know the term “chronic Lyme” is a conversation stopper in some…

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The Early Dissemination Defect Attributed to Disruption of Decorin-Binding Proteins Is Abolished in Chronic Murine Lyme Borreliosis

doi: 10.1128/IAI.01359-12 Infect. Immun. May 2013 vol. 81 no. 5 1663-1673    Denise M. Imaia, D. Scott Samuelsb, Sunlian Fenga, Emir Hodzica, Kim Olsena and Stephen W. Bartholda Center for Comparative Medicine, Schools of Medicine and Veterinary Medicine, University of California at Davis, Davis, California, USAa Division of Biological Sciences, The University of Montana, Missoula, Montana, USAb R. P. Morrison, Editor + Author…