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  • International News | Lyme Controversy

    Government agency is delaying report on [Lyme] disease, treatments

    ByCanLyme Team December 31, 2012April 21, 2023

    Sturbridge activist seeks release of Lyme disease report   STURBRIDGE [Massachusetts] – A Lyme disease activist and sufferer claims two high-ranking state Department of Public Health officials are stalling the release of a report that could shed more light on the disease. Patricia A. McCleary of Sturbridge said state epidemiologist Dr. Al DeMaria and state veterinarian…

    Read More Government agency is delaying report on [Lyme] disease, treatmentsContinue

  • Guidelines - Boxing-in disease | Lyme Controversy | Voices on Lyme

    Guidelines: Guides to Profit? [Money talks]

    ByCanLyme Team December 19, 2012April 21, 2023

    By John Fauber, Milwaukee Journal Sentinel/Medpage Today and Ellen  Gabler, Milwaukee Journal Sentinel Published: December 19, 2012 The stated intent of treatment guidelines is to “guide” clinicians’ treatment of patients with a series of recommendations based on evidence. But that intent may not be universally reflected in published guidelines and the disconnect is all about…

    Read More Guidelines: Guides to Profit? [Money talks]Continue

  • Featured | Research

    Transovarial transmission of Borrelia spirochetes by Ixodes scapularis: A summary of the literature and recent observations.

    ByCanLyme Team December 17, 2012April 21, 2023

    Rollend L, Fish D, Childs JE. Yale School of Public Health, 60 College Street, New Haven, CT 06520-8034, USA. Electronic address: Lindsay [dot] Rollend [at] yale [dot] edu. Abstract Transovarial transmission (TOT) of Borrelia burgdorferi (sensu lato), the agent of Lyme disease, by the Ixodes persulcatus group of hard ticks (Ixodidae) has frequently been reported…

    Read More Transovarial transmission of Borrelia spirochetes by Ixodes scapularis: A summary of the literature and recent observations.Continue

  • Medical Publications | Research

    (case report) Lyme Neuroborreliosis Manifesting as an Intracranial Mass Lesion

    ByCanLyme Team December 16, 2012April 21, 2023

    Neurosurgery Issue: Volume 30(5), May 1992, p 769-773 Copyright: Copyright (C) by the Congress of Neurological Surgeons Publication Type: [Case Report] ISSN: 0148-396X Accession: 00006123-199205000-00021 Keywords: Lyme disease, Stereotaxis [Case Report] Lyme Neuroborreliosis Manifesting as an Intracranial Mass Lesion Murray, Rhett M.D.; Morawetz, Richard M.D.; Kepes, John M.D.; El Gammal, Taher M.D.; LeDoux, Mark M.D….

    Read More (case report) Lyme Neuroborreliosis Manifesting as an Intracranial Mass LesionContinue

  • Medical Publications | Research

    Transovarial transmission of Borrelia spirochetes by Ixodes scapularis: A summary of the literature and recent observations.

    ByCanLyme Team December 15, 2012April 21, 2023

    Ticks Tick Borne Dis. 2012 Dec 10. pii: S1877-959X(12)00067-2. doi: 10.1016/j.ttbdis.2012.06.008. [Epub ahead of print] Rollend L, Fish D, Childs JE. Source Yale School of Public Health, 60 College Street, New Haven, CT 06520-8034, USA. Electronic address: Lindsay [dot] Rollend [at] yale [dot] edu Abstract Transovarial transmission (TOT) of Borrelia burgdorferi (sensu lato), the agent…

    Read More Transovarial transmission of Borrelia spirochetes by Ixodes scapularis: A summary of the literature and recent observations.Continue

  • Medical Publications | Research

    Complement regulator-acquiring surface proteins of Borrelia burgdorferi: Structure, function and regulation of gene expression.

    ByCanLyme Team December 14, 2012April 21, 2023

    Kraiczy P, Stevenson B. Source Institute of Medical Microbiology and Infection Control, Frankfurt University Hospital, Paul-Ehrlich-Str. 40, D-60596 Frankfurt, Germany. Electronic address: Kraiczy [at] em [dot] uni-frankfurt [dot] de. Abstract Borrelia burgdorferi, the etiological agent of Lyme disease, exploits an array of strategies to establish infection and to overcome host innate and adaptive immune responses….

    Read More Complement regulator-acquiring surface proteins of Borrelia burgdorferi: Structure, function and regulation of gene expression.Continue

  • Medical Publications | Research

    High-Throughput Screening Identifies Three Inhibitor Classes of the Telomere Resolvase from the Lyme Disease Spirochete

    ByCanLyme Team December 14, 2012April 21, 2023

    Abstract Lyme disease, the most common vector-borne zoonosis in North America, is caused by the spirochetal pathogen Borrelia burgdorferi. The telomere resolvase encoded by this organism (ResT) promotes the formation of covalently closed hairpin ends on the linear DNA molecules of B. burgdorferi through a two-step transesterification. ResT is essential for survival and is therefore…

    Read More High-Throughput Screening Identifies Three Inhibitor Classes of the Telomere Resolvase from the Lyme Disease SpirocheteContinue

  • Medical Publications | Research

    Vascular binding of a pathogen under shear force through mechanistically distinct sequential interactions with host macromolecules.

    ByCanLyme Team December 14, 2012April 21, 2023

    Mol Microbiol. 2012 Dec;86(5):1116-31. doi: 10.1111/mmi.12045. Epub  2012 Oct 24. Moriarty TJ, Shi M, Lin YP, Ebady R, Zhou H, Odisho T, Hardy PO, Salman-Dilgimen A, Wu J, Weening EH, Skare JT, Kubes P, Leong J, Chaconas G. Source Matrix Dynamics Group, Faculty of Dentistry, and Department of Laboratory Medicine and Pathobiology, Faculty of Medicine,…

    Read More Vascular binding of a pathogen under shear force through mechanistically distinct sequential interactions with host macromolecules.Continue

  • Medical Publications | Research

    Analysis of an Ordered, Comprehensive STM Mutant Library in Infectious Borrelia burgdorferi: Insights into the Genes Required for Mouse Infectivity.

    ByCanLyme Team December 14, 2012April 21, 2023

    PLoS One. 2012;7(10):e47532. doi: 10.1371/journal.pone.0047532. Epub  2012 Oct 25. Lin T, Gao L, Zhang C, Odeh E, Jacobs MB, Coutte L, Chaconas G, Philipp MT, Norris SJ. Source Department of Pathology and Laboratory Medicine, Medical School, University of Texas Health Science Center at Houston, Houston, Texas, United States of America. Abstract The identification of genes…

    Read More Analysis of an Ordered, Comprehensive STM Mutant Library in Infectious Borrelia burgdorferi: Insights into the Genes Required for Mouse Infectivity.Continue

  • Medical Publications | Research

    CSM murray award lecture – functional studies of the Lyme disease spirochete – from molecules to mice.

    ByCanLyme Team December 14, 2012April 21, 2023

    Abstract Lyme borreliosis, also known as Lyme disease, is now the most common vector transmitted disease in the northern hemisphere. It is caused by the spirochete  Borrelia burgdorferi  and related species. In addition to their clinical importance, these organisms are fascinating to study because of the wide variety of unusual features they possess. Ongoing work…

    Read More CSM murray award lecture – functional studies of the Lyme disease spirochete – from molecules to mice.Continue

  • Medical Publications | Research

    Acute polyradiculoneuritis syndrome: clinical observations and differential diagnosis [important to rule out Lyme disease].

    ByCanLyme Team December 13, 2012April 21, 2023

    Authors: Supanc V, Stojić I, Vargek-Solter V, Breitenfeld T, Roje-Bedeković M and Demarin V Citation: Acta Clin Croat 2012(Jun); 51(2): 195-9. Location: University Department of Neurology, Sestre milosrdnice University Hospital Center, Zagreb, Croatia. visnjasupanc [at] inet [dot] hr Guillain-Barré syndrome (GBS) and neuroborreliosis may clinically manifest with symptoms related to acute polyradiculoneuritis. The aim and…

    Read More Acute polyradiculoneuritis syndrome: clinical observations and differential diagnosis [important to rule out Lyme disease].Continue

  • Research

    First isolation of Lyme disease spirochete, Borrelia burgdorferi, from blacklegged tick, Ixodes scapularis, removed from a bird in nova Scotia, Canada.

    ByCanLyme Team December 12, 2012April 21, 2023

    The Lyme disease spirochete, Borrelia burgdorferi, has been isolated from a blacklegged tick, Ixodes scapularis, removed from a songbird in Canada. On 28 May 1999, this engorged blacklegged tick nymph was removed from a common yellowthroat, Geothlypis trichas, collected during bird banding on Bon Portage Island, Nova Scotia. The Atlantic Bird Observatory participated in collecting…

    Read More First isolation of Lyme disease spirochete, Borrelia burgdorferi, from blacklegged tick, Ixodes scapularis, removed from a bird in nova Scotia, Canada.Continue

  • Miscellaneous | Research

    Birds disperse ixodid (Acari: Ixodidae) and Borrelia burgdorferi-infected ticks in Canada

    ByCanLyme Team December 12, 2012April 21, 2023

    Scott JD, Fernando K, Banerjee SN, Durden LA, Byrne SK, Banerjee M, Mann RB, Morshed MG. Source Lyme Disease Association of Ontario, Fergus, Canada Abstract A total of 152 ixodid ticks (Acari: Ixodidae) consisting of nine species was collected from 82 passerine birds (33 species) in 14 locations in Canada from 1996 to 2000. The…

    Read More Birds disperse ixodid (Acari: Ixodidae) and Borrelia burgdorferi-infected ticks in CanadaContinue

  • Miscellaneous

    Migratory songbirds disperse ticks across Canada, and first isolation of the Lyme disease spirochete, Borrelia burgdorferi, from the avian tick, Ixodes auritulus.

    ByCanLyme Team December 12, 2012April 21, 2023

    Abstract During a 3-yr comprehensive study, 196 ixodid ticks (9 species) were collected from 89 passerine birds (32 species) from 25 localities across Canada to determine the distribution of avian-associated tick species and endogenous Lyme disease spirochetes, Borrelia burgdorferi Johnson, Schmid, Hyde, Steigerwalt, and Brenner. We report the following first records of tick parasitism on…

    Read More Migratory songbirds disperse ticks across Canada, and first isolation of the Lyme disease spirochete, Borrelia burgdorferi, from the avian tick, Ixodes auritulus.Continue

  • Medical Publications | Research

    Misinformation sent to all Nova Scotia MLA’s and MP’s by Chief Medical Officer of Nova Scotia, Robert Strang.

    ByCanLyme Team December 12, 2012April 21, 2023

    Here you can read the letter from Dr. Strang at, Strang MLA’s/MP’s followed below by a copy of our reply that was also sent to all Nova Scotia politicians, federal and provincial. Dr. Strang acted in a manner that is contrary to the principles of open science in that he deliberately did not mention the…

    Read More Misinformation sent to all Nova Scotia MLA’s and MP’s by Chief Medical Officer of Nova Scotia, Robert Strang.Continue

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