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  • Medical Publications | Research

    Evolving Perspectives on Lyme Borreliosis in Canada

    ByCanLyme Team December 11, 2012April 21, 2023

    Abstract: With cases now documented in every province, Lyme borreliosis (LB) is emerging as a serious public health risk in Canada. Controversy over the contribution of LB to the burden of chronic disease is maintained by difficulty in capturing accurate Canadian statistics, especially early clinical cases of LB. The use of dogs as sentinel species…

    Read More Evolving Perspectives on Lyme Borreliosis in CanadaContinue

  • Medical Publications | Research

    Plaques of Alzheimer’s disease originate from cysts of Borrelia burgdorferi, the Lyme disease spirochete

    ByCanLyme Team December 7, 2012April 21, 2023

    Summary Here is hypothesized a truly revolutionary notion that rounded cystic forms of Borrelia burgdorferi are the root cause of the rounded structures called plaques in the Alzheimer brain. Rounded ‘‘plaques’ in high density in brain tissue are emblematic of Alzheimer’s disease (AD). Plaques may be conceptualized as rounded ‘‘pock mark-like’’ areas of brain tissue…

    Read More Plaques of Alzheimer’s disease originate from cysts of Borrelia burgdorferi, the Lyme disease spirocheteContinue

  • International News | Medical Publications | Research

    Prevent Lyme Disease with Showers and Fences [Yale study]

    ByCanLyme Team December 6, 2012April 21, 2023

    Infection can cause complications if not treat early, but research suggests you can prevent Lyme disease with some simple tactics. RODALE NEWS, EMMAUS, PA–In the Northeastern United States, the place where you’re most likely to be bitten by a tick carrying Lyme disease is not in the woods, but in your own backyard. Fortunately, research…

    Read More Prevent Lyme Disease with Showers and Fences [Yale study]Continue

  • International News | Medical Publications

    Off-the-Charts Anxiety: Is a Tick Bite Making You Nuts?

    ByCanLyme Team December 6, 2012April 21, 2023

    Tick-borne infections aren’t just causing sore joints and swollen knees. Some cause psychiatric symptoms that often go untreated, some experts say. “…tick-borne infections could actually trigger panic attacks and other psychiatric disorders in some people. “After treating thousands of patients with tick-borne disease in the past 20 years, it appears psychiatric symptoms are more commonly…

    Read More Off-the-Charts Anxiety: Is a Tick Bite Making You Nuts?Continue

  • Medical Publications | Research

    Biofilms: A New Hideout for Borrelia burgdorferi?

    ByCanLyme Team December 4, 2012April 21, 2023

    The University of New Haven established a Lyme Disease Research group six years ago. To date, over forty graduate students have received training in Lyme disease related research. One of our recent projects studies the different formations of Borrelia burgdorferi, the Lyme disease bacteria. With coauthor Dr. Alan MacDonald, we recently suggested that Borrelia burgdorferi…

    Read More Biofilms: A New Hideout for Borrelia burgdorferi?Continue

  • Medical Publications | Miscellaneous | Research

    Evaluation of in-vitro antibiotic susceptibility of different morphological forms of Borrelia burgdorferi

    ByCanLyme Team December 4, 2012April 21, 2023

    Background: Lyme disease is a tick-borne illness caused by the spirochete Borrelia burgdorferi. Although antibiotic therapy is usually effective early in the disease, relapse may occur when administration of antibiotics is discontinued. Studies have suggested that resistance and recurrence of Lyme disease might be due to formation of different morphological forms of B. burgdorferi, namely…

    Read More Evaluation of in-vitro antibiotic susceptibility of different morphological forms of Borrelia burgdorferiContinue

  • International News | Medical Publications | Research

    There will likely never be a Lyme vaccine says researcher Alan Barbour.

    ByCanLyme Team December 4, 2012April 21, 2023

    Why some strains of Lyme disease bacteria are common and others are not Findings could lead to novel strategy to control disease New clues about the bacteria that cause Lyme disease could lead to a novel strategy to reduce infections, according to a study to be published in mBio®, the online open-access journal of the…

    Read More There will likely never be a Lyme vaccine says researcher Alan Barbour.Continue

  • Medical Publications | Research

    Updates on Borrelia burgdorferi sensu lato complex with respect to public health

    ByCanLyme Team December 3, 2012April 21, 2023

    Summary Borrelia burgdorferi sensu lato (s.l.) complex is a diverse group of worldwide distributed bacteria that includes 18 named spirochete species and a still not named group proposed as genomospecies 2 (Postic et al., 2007). Descriptions of new species and variants continue to be recognized, so the current number of described species is probably not…

    Read More Updates on Borrelia burgdorferi sensu lato complex with respect to public healthContinue

  • Medical Publications | Research

    Multilocus sequence analysis of Borrelia bissettii strains from North America reveals a new Borrelia species, Borrelia kurtenbachii

    ByCanLyme Team December 3, 2012April 21, 2023

    Gabriele Margos,a,* Andrias Hojgaard,b Robert S. Lane,c Muriel Cornet,d Volker Fingerle,e Nataliia Rudenko,f Nicholas Ogden,g David M. Aanensen,h Durland Fish,i and Joseph Piesman,b Abstract Using multilocus sequence analyses (MLSA), we investigated the phylogenetic relationship of spirochaete strains from North America previously assigned to the genospecies Borrelia bissettii. We amplified internal fragments of 8 housekeeping genes…

    Read More Multilocus sequence analysis of Borrelia bissettii strains from North America reveals a new Borrelia species, Borrelia kurtenbachiiContinue

  • International News | Medical Publications | Research

    Humans Infected with Relapsing Fever Spirochete Borrelia miyamotoi, Russia

    ByCanLyme Team December 3, 2012April 21, 2023

    Abstract Borrelia miyamotoi is distantly related to B. burgdorferi and transmitted by the same hard-body tick species. We report 46 cases of B. miyamotoi infection in humans and compare the frequency and clinical manifestations of this infection with those caused by B. garinii and B. burgdorferi infection. All 46 patients lived in Russia and had…

    Read More Humans Infected with Relapsing Fever Spirochete Borrelia miyamotoi, RussiaContinue

  • Medical Publications | Research

    Detection of Borrelia bissettii in cardiac valve tissue of a patient with endocarditis and aortic valve stenosis in the Czech Republic.

    ByCanLyme Team December 3, 2012April 21, 2023

    Nataliia Rudenko Maryna Golovchenko Aleš Mokráček Natalja Piskunová Daniel Růžek Nadja Mallatová Libor Grubhoffer ABSTRACT Molecular analysis of a clinical sample confirmed the presence of Borrelia bissettii DNA in cardiac valve tissue from a patient with endocarditis and aortic valve stenosis. This evidence strongly supports the involvement of B. bissettii in Lyme disease in Europe. Read…

    Read More Detection of Borrelia bissettii in cardiac valve tissue of a patient with endocarditis and aortic valve stenosis in the Czech Republic.Continue

  • Updates

    Nouveau-Brunswick: le risque de contracter la maladie de Lyme en hausse

    ByCanLyme Team December 1, 2012April 21, 2023

    La Presse Canadienne Fredericton Le risque de contracter la maladie de Lyme est en hausse au Nouveau-Brunswick, selon des chercheurs de l’Université de Mount Allison. La biologiste Vett Lloyd a indiqué que les tiques à pattes noires capturées montrent des taux d’infection étonnamment rares et élevés. Mme Lloyd soutient qu’environ 40% de ces tiques, qui…

    Read More Nouveau-Brunswick: le risque de contracter la maladie de Lyme en hausseContinue

  • Medical Publications | Research

    Reservoir Competence of Wildlife Host Species for Babesia microti.

    ByCanLyme Team November 27, 2012April 21, 2023

    Hersh MH, Tibbetts M, Strauss M, Ostfeld RS, Keesing F. Emerging Infectious Diseases, 2012 Dec; 18(12): 1951-7. Abstract Human babesiosis is an increasing health concern in the northeastern United States, where the causal agent, Babesia microti, is spread through the bite of infected Ixodes scapularis ticks. We sampled 10 mammal and 4 bird species within…

    Read More Reservoir Competence of Wildlife Host Species for Babesia microti.Continue

  • Medical Publications | Research

    Bartonella henselae endocarditis of percutaneously implanted pulmonary valve.

    ByCanLyme Team November 27, 2012April 21, 2023

    J Heart Valve Dis. 2011 Jan;20(1):94-7. Atamanyuk I, Raja SG, Kostolny M. Source Department of Paediatric Cardiothoracic Surgery, Great Ormond Street Hospital, London, United Kingdom. Abstract Percutaneous pulmonary valve implantation (PPVI) has revolutionized the management of right ventricular outflow tract dysfunction after repaired congenital heart disease. The technology is considered to be safe, with a…

    Read More Bartonella henselae endocarditis of percutaneously implanted pulmonary valve.Continue

  • Medical Publications | Research

    Detection and heterogeneity of Borrelia burgdorferi in Ixodes ticks by culture-dependent and culture-independent methods

    ByCanLyme Team November 27, 2012April 21, 2023

    Authors:   Xu G, Wesker J, White C, Campbell J, Reich NG and Rich SM Citation:   J. Clin. Microbiol. 2012(Nov) Location:  Laboratory of Medical Zoology, Department of Microbiology, University of Massachusetts, Amherst, MA 01003, USA. DOI: 10.1128/JCM.03009-12 Abstract Ability to detect heterogeneity of ospC genotypes of the Lyme disease spirochete, Borrelia burgdorferi, in the tick vector…

    Read More Detection and heterogeneity of Borrelia burgdorferi in Ixodes ticks by culture-dependent and culture-independent methodsContinue

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