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A Borrelia burgdorferi surface-exposed transmembrane protein lacking detectable immune responses supports pathogen persistence and constitutes a vaccine target.

Kung F, Kaur S, Smith AA, Yang X, Wilder CN, Sharma K, Buyuktanir O, Pal U. The Journal of Infectious Diseases, online first 2016 Jan 7. Abstract Borrelia burgdorferi harbors a limited set of transmembrane surface proteins, most of which constitute key targets of humoral immune responses. Here we show that BB0405, a conserved membrane-spanning…

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USA CDC : Vaccines for Lyme Disease – Past, Present, and Future

[CanLyme note: The argument to market a vaccine anytime soon is weak.  Until many eyes have had a chance to review the data, primarily including the patient’s experts, no vaccine should be introduced… and if it is, it will fail because of broken trust.] Published on Jul 30, 2015 A Lyme disease vaccine is no…

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Researchers strive for vaccine against tick-borne diseases

[CanLyme note: notice that most USA National Institute of Health funding only goes to find a way of monetizing Lyme disease so that companies can profit off of the sick. Virtually no research is funded to identify the prevalence in the current population of the chronically ill, who have been given everything but a Lyme…