Whole genome sequencing of human Borrelia burgdorferi isolates reveals linked blocks of accessory genome elements located on plasmids and associated with human dissemination
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Whole genome sequencing of human Borrelia burgdorferi isolates reveals linked blocks of accessory genome elements located on plasmids and associated with human dissemination

ByCanLyme Team

Using genetic association study methods, we identify an accessory genome signature associated with dissemination in humans and define the individual plasmids and genes that make up this signature.

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Pathogenic analysis of Borrelia garinii strain SZ isolated from northeastern China

ByTeam

BACKGROUND: Various genospecies of Borrelia burgdorferi sensu lato (s.l.) have been identified from patients and animals worldwide. Genospecies-related dissemination of disease has been reported. The present study aimed to elucidate the pathogenicity of infections caused by B. garinii SZ isolated in China. B. burgdorferi B31 and B. afzelii BO23 were used for comparison. METHODS: Spirochete…

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The Early Dissemination Defect Attributed to Disruption of Decorin-Binding Proteins Is Abolished in Chronic Murine Lyme Borreliosis

ByTeam

doi: 10.1128/IAI.01359-12 Infect. Immun. May 2013 vol. 81 no. 5 1663-1673    Denise M. Imaia, D. Scott Samuelsb, Sunlian Fenga, Emir Hodzica, Kim Olsena and Stephen W. Bartholda Center for Comparative Medicine, Schools of Medicine and Veterinary Medicine, University of California at Davis, Davis, California, USAa Division of Biological Sciences, The University of Montana, Missoula, Montana, USAb R. P. Morrison, Editor + Author…