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Anaplasmosis: An emerging tick-borne disease of importance in Canada

Abstract Human Granulocytic Anaplasmosis (HGA) is an infection caused by the intracellular bacterium Anaplasma phagocytophilum. As a tick-borne disease, the public health impact of HGA continues to increase with range expansion of the disease vector. The clinical presentation of HGA is often a non-specific febrile illness. The presence of leukopenia, thrombocytopenia, and mild hepatic injury are frequently noted…

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An Atypical Presentation of a Severe Case of Anaplasma Phagocytophilum

March 2022 Abstract We report a case of a 79-year-old male presenting to a South Bronx hospital with complaints of fever, shortness of breath, severe thrombocytopenia, hematuria, elevated liver enzymes, and acute renal failure. The patient rapidly progressed to acute hypoxic respiratory failure requiring mechanical ventilation. Treatment was delayed for six days because the tick-borne…


High-throughput screening of tick-borne pathogens in Europe

Lorraine Michelet; Sabine Delannoy; Elodie Devillers; Gérald Umhang; Anna Aspan; Mikael Juremalm; Jan Chirico; Fimme J. van der Wal; Hein Sprong; Thomas P. Boye Pihl; Kirstine Klitgaard; Rene Bødker; Patrick Fach; Sara Moutailler Due to increased travel, climatic, and environmental changes, the incidence of tick-borne disease in both humans and animals is increasing throughout Europe….

Unique strains of Anaplasma phagocytophilum segregate among diverse questing and non-questing Ixodes tick species in the western United States

Abstract The emerging tick-borne pathogen Anaplasma phagocytophilum infects humans, domestic animals, and wildlife throughout the Holarctic. In the western US, the ecology of A. phagocytophilum is particularly complex, with multiple pathogen strains, tick vectors, and reservoir hosts. A recent phylogenetic analysis of A. phagocytophilum strains isolated from various small mammal hosts in California documented distinct…

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Detection of human bacterial pathogens in ticks collected from Louisiana black bears (Ursus americanus luteolus).

Ticks Tick Borne Dis. 2013 Apr;4(3):191-6. doi: 10.1016/j.ttbdis.2012.12.002. Epub  2013 Feb 15. Leydet BF Jr, Liang FT. Source Department of Pathobiological Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA, USA. Electronic address: bleyde1@tigers.lsu.edu. Abstract There are 4 major human-biting tick species in the northeastern United States, which include: Amblyomma americanum, Amblyomma maculatum,…