Regional Cerebral Blood Flow and Metabolic Rate in Persistent Lyme Encephalopathy
There is controversy regarding whether objective neurobiological abnormalities exist after intensive antibiotic treatment for Lyme disease.
A Twist On Lyme: The Challenge of Diagnosing European Lyme Neuroborreliosis
Lyme neuroborreliosis is a tick-borne illness with central and peripheral nervous system manifestations. Clinical features and methods for accurate diagnosis differ across world regions owing to different causative Borrelia species. The importance of these distinctions is highlighted by a 12 year old Canadian girl who acquired Lyme neuroborreliosis in Europe.
Lyme and Tick-borne Diseases Research Center – Message from the Director
This is both a disturbing and an exciting time in the world of Lyme disease. Disturbing because the medical and public health communities have failed to stem the steady increase in the number of cases of Lyme disease over the last 2 decades – with an expansion of over 35% between 2006-2007 alone. Exciting because advances in medical technology are leading to breakthroughs in how we understand this disease.
Infectious Disease Treatment Guidelines Weakened By Paucity of Scientific Evidence
November 13, 2009 (Philadelphia, Pennsylvania) – Two separate analyses presented here at the Infectious Diseases Society of America (IDSA) 47th Annual Meeting revealed that most of the society’s treatment guidelines are based on expert opinion, nonrandomized trials, and case studies.
Doctors must be allowed to contribute to policy debate without fear. Current system stifles MDs speaking out publicly on their concerns
Medical doctors have a great deal to contribute to public policy debates. But the systems that have developed within the profession and within government stifle public debate among doctors and attempt to create a phoney unity that works against the public interest, as we are slowly learning.
Evidence based medicine, not always best evidence.
Evidence Based Medicine began as a “bottom-up” paradigm that taught medical residents to search the literature for the best available evidence and to critically appraise it for making patient care decisions.
The challenge of Lyme disease: tired of the Lyme wars
Few diseases have aroused more emotional attention in the press and the public than Lyme disease.
LYMEPOLICYWONK: Was this important Lyme study hidden for 12 years?
The recently published monkey study by Embers and colleagues regarding the persistence of Lyme after antibiotic treatment is important for two distinct reasons.
The Lyme Disease Controversy
The CDC clinical criteria for Lyme Disease which exist for the purpose of monitoring the rate of Lyme disease nationally are quite narrowly defined in order to ensure a high degree of specificity in the diagnosis
Chronic Lyme Disease in British Columbia
A review of Strategic and Policy Issues
Lyme by far most common cause of pediatric meningitis & has distinctive characteristics
Lyme meningitis, the major cause of childhood meningitis in an endemic area: A population based study
Spirochetes observed in the brain in more than 90% of Alzheimer disease cases.
Alzheimer’s disease – a neurospirochetosis. Analysis of the evidence following Koch’s and Hill’s criteria
Improved Clinical Sensitivity for Detection of Antibodies to Borrelia burgdorferi
Improved Clinical Sensitivity for Detection of Antibodies to Borrelia burgdorferi by Western Blots Prepared from a Mixture of Two Strains of B. burgdorferi, 297 and B31, and Interpreted by In-house Criteria
Antibiotic susceptibility of different morphological forms of Borrelia burgdorferi
Lyme disease is a tick-borne illness caused by the spirochete Borrelia burgdorferi.
Although antibiotic therapy is usually effective early in the disease, relapse may occur when
administration of antibiotics is discontinued.Biology and neuropathology of dementia in syphilis and Lyme disease
It has long been known that Treponema pallidum, subspecies pallidum can in late stages of neurosyphilis cause dementia, cortical atrophy, and amyloid deposi- tion. The occurrence of dementia, including subacute presenile dementia, was also reported in association with Lyme disease caused by another spirochete, Borrelia burgdorferi.