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Spirochetes causing Lyme borreliosis are obligate parasites that can only be found in a tick vector or a vertebrate host. The ability to survive in these two disparate environments requires up and downregulation of specific genes by regulatory circuits that remain largely obscure.
Persistent infection by pathogenic organisms requires effective strategies for the defense of these organisms against the host immune response.
Here we investigate the dynamics of the hepatic intravascular immune response to a pathogen relevant to invariant natural killer T cells (iNKT cells).
The source of sporadic Lyme disease (Lyme borreliosis) across Canada has been a mystery. Several tenets abound about the origin of this bacterial illness, but science is often lacking.
Scott JD, Anderson JF, Durden LA J Parasitol 2011 08 24 Abstract Millions of Lyme disease vector ticks are dispersed annually by songbirds across Canada, but often overlooked as the source of infection. For clarity on vector distribution, we sampled 481 ticks (12 species and 3 undetermined ticks) from 211 songbirds (42 species/subspecies) nationwide. Using…
Benjamin Luft, M.D., Professor of Medicine, Stony Brook University Medical Center, and a team of medical researchers have determined the genetic blueprint of 13 strains of the bacteria that cause Lyme disease. The finding is crucial to advancing research on Lyme disease, the most frequent tick-borne infection in North America and Europe, and may lead to better diagnostics and a vaccine
Borrelia burgdorferi is a causative agent of Lyme disease in North America and Eurasia. The first complete genome sequence of B. burgdorferi strain 31, available for more than a decade, has assisted research on the pathogenesis of Lyme disease.
Department of Biochemistry & Molecular Biology, and Department of Microbiology & Infectious Diseases, University of Calgary
Dog Diseases number in the scores, just as in humans. But, veterinarians tend to see some much more than others. Sadly, a great deal of grief could be avoided if more dog owners were careful to see that their pets are immunized regularly against preventable dog diseases.
Veterinarians are recommending that pets be vaccinated against the deer tick because the number of pests carrying Lyme disease is on the rise in southeastern New Brunswick.
In Canada, the environmental suitability for Borrelia burgdorferi and Anaplasma phagocytophilum vectors, Ixodes scapularis and Ixodes pacificus, appears to be growing. In 1991, there was one known endemic location for I. scapularis while currently there are at least eleven. An estimated 8–12% of the 50–175 million adventitious I. scapularis ticks that enter Canada on birds are positive for B. burgdorferi.
I am a scientist and a Lyme disease sufferer, and I am writing to warn you about the realities of Lyme disease, and the failure of our governments to acknowledge its prevalence in Canada. This story is filled with controversy, I am one of its victims, and I am far from alone.
Magnotta is Ontario’s third largest winery and the only company of its kind in Canada licensed to produce and sell wine, beer and distilled products. With over 3,500 awards to date for product excellence, Magnotta is Canada’s most award winning winery.
By Gerry Bellett, Vancouver Sun, August 6, 2009 8:01 PM Dr. LaVerne Clifford Kindree has been admitted to the Order of Canada in recognition for more than 50 years of public service in Squamish, which in its length and depth can only be described as astonishing. The citation for the award gives an indication of…
Committee on Lyme Disease and Other Tick-Borne Diseases: The State of the Science; Institute of Medicine
The Canadian Lyme Disease Foundation is dedicated to promoting research, education, diagnosis and treatment of Lyme and associated diseases.
