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The Platelet Fraction Is a Novel Reservoir to Detect Lyme Borrelia in Blood

October 29th, 2021 Victoria P Sanderson 1, Iain L Mainprize 1, Lisette Verzijlenberg 1, Cezar M Khursigara 2, Melanie K B Wills 1 Abstract Serological diagnosis of Lyme disease suffers from considerable limitations. Yet, the technique cannot currently be replaced by direct detection methods, such as bacterial culture or molecular analysis, due to their inadequate sensitivity. The low bacterial burden in vasculature and lack…