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Infection can cause complications if not treat early, but research suggests you can prevent Lyme disease with some simple tactics. RODALE NEWS, EMMAUS, PA–In the Northeastern United States, the place where you’re most likely to be bitten by a tick carrying Lyme disease is not in the woods, but in your own backyard. Fortunately, research…
The University of New Haven established a Lyme Disease Research group six years ago. To date, over forty graduate students have received training in Lyme disease related research. One of our recent projects studies the different formations of Borrelia burgdorferi, the Lyme disease bacteria. With coauthor Dr. Alan MacDonald, we recently suggested that Borrelia burgdorferi…
Background: Lyme disease is a tick-borne illness caused by the spirochete Borrelia burgdorferi. Although antibiotic therapy is usually effective early in the disease, relapse may occur when administration of antibiotics is discontinued. Studies have suggested that resistance and recurrence of Lyme disease might be due to formation of different morphological forms of B. burgdorferi, namely…
Why some strains of Lyme disease bacteria are common and others are not Findings could lead to novel strategy to control disease New clues about the bacteria that cause Lyme disease could lead to a novel strategy to reduce infections, according to a study to be published in mBio®, the online open-access journal of the…
Summary Borrelia burgdorferi sensu lato (s.l.) complex is a diverse group of worldwide distributed bacteria that includes 18 named spirochete species and a still not named group proposed as genomospecies 2 (Postic et al., 2007). Descriptions of new species and variants continue to be recognized, so the current number of described species is probably not…
Gabriele Margos,a,* Andrias Hojgaard,b Robert S. Lane,c Muriel Cornet,d Volker Fingerle,e Nataliia Rudenko,f Nicholas Ogden,g David M. Aanensen,h Durland Fish,i and Joseph Piesman,b Abstract Using multilocus sequence analyses (MLSA), we investigated the phylogenetic relationship of spirochaete strains from North America previously assigned to the genospecies Borrelia bissettii. We amplified internal fragments of 8 housekeeping genes…
Abstract Borrelia miyamotoi is distantly related to B. burgdorferi and transmitted by the same hard-body tick species. We report 46 cases of B. miyamotoi infection in humans and compare the frequency and clinical manifestations of this infection with those caused by B. garinii and B. burgdorferi infection. All 46 patients lived in Russia and had…
Nataliia Rudenko Maryna Golovchenko Aleš Mokráček Natalja Piskunová Daniel Růžek Nadja Mallatová Libor Grubhoffer ABSTRACT Molecular analysis of a clinical sample confirmed the presence of Borrelia bissettii DNA in cardiac valve tissue from a patient with endocarditis and aortic valve stenosis. This evidence strongly supports the involvement of B. bissettii in Lyme disease in Europe. Read…
Hersh MH, Tibbetts M, Strauss M, Ostfeld RS, Keesing F. Emerging Infectious Diseases, 2012 Dec; 18(12): 1951-7. Abstract Human babesiosis is an increasing health concern in the northeastern United States, where the causal agent, Babesia microti, is spread through the bite of infected Ixodes scapularis ticks. We sampled 10 mammal and 4 bird species within…
J Heart Valve Dis. 2011 Jan;20(1):94-7. Atamanyuk I, Raja SG, Kostolny M. Source Department of Paediatric Cardiothoracic Surgery, Great Ormond Street Hospital, London, United Kingdom. Abstract Percutaneous pulmonary valve implantation (PPVI) has revolutionized the management of right ventricular outflow tract dysfunction after repaired congenital heart disease. The technology is considered to be safe, with a…
Authors: Xu G, Wesker J, White C, Campbell J, Reich NG and Rich SM Citation: J. Clin. Microbiol. 2012(Nov) Location: Laboratory of Medical Zoology, Department of Microbiology, University of Massachusetts, Amherst, MA 01003, USA. DOI: 10.1128/JCM.03009-12 Abstract Ability to detect heterogeneity of ospC genotypes of the Lyme disease spirochete, Borrelia burgdorferi, in the tick vector…
Abstract All reported cases of WA1 babesiosis have occurred in the Pacific coast region of the United States, suggesting that WA1 is limited to this geographic area. However, we detected WA1 IgG in 27% of clinical sera sent to our laboratory for WA1 IgG testing from across the United States over a 2-year period, suggesting…
Abstract Borrelia burgdorferi, the causative agent of Lyme disease, has long been known to be capable of forming aggregates and colonies. It was recently demonstrated that Borrelia burgdorferi aggregate formation dramatically changes the in vitro response to hostile environments by this pathogen. In this study, we investigated the hypothesis that these aggregates are indeed…
Abstract Background The long latent stage seen in syphilis, followed by chronic central nervous system infection and inflammation, can be explained by the persistence of atypical cystic and granular forms of Treponema pallidum. We investigated whether a similar situation may occur in Lyme neuroborreliosis. Method Atypical forms of Borrelia burgdorferi spirochetes were induced exposing cultures…
Summary Systemic dissemination of microbial pathogens permits microbes to spread from the initial site of infection to secondary target tissues and is responsible for most mortality due to bacterial infections. Dissemination is a critical stage of disease progression by the Lyme spirochaete, Borrelia burgdorferi. However, many mechanistic features of the process are not yet understood….
The Canadian Lyme Disease Foundation is dedicated to promoting research, education, diagnosis and treatment of Lyme and associated diseases.
