The immune system cannot generate immunological memory during infection with the Lyme disease agent B. burgdorferi
R.A. Elsner, S.W. Barthold, N. Baumgarth Graduate Group in Microbiology and the Center for Comparative Medicine, University of California-Davis, Davis, CA, USA In vertebrates including humans, mice and dogs, the bacteria Borrelia burgdorferi (Bb) causes a chronic, non-resolving infection known as Lyme disease, which requires antibiotic treatment to clear the bacteria. Re-infections are common in endemic regions. Similarly, mice…