Medical Publications & Research

Canadian Lyme treatment guidelines have changed dramatically in the past few years. CanLyme is dedicated to promoting accurate and up-to-date medical information.

The article abstracts below have primarily been sourced from: PubMed.gov or the specific journal in which they were published. Please click the PubMed or journal link to read the whole article on their site.

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Recent in: Medical Publications

New York State Grants Approval for IGeneX’s Newly Developed Tick-Borne Relapsing Fever (TBRF) ImmunoBlot Tests

[CanLyme Note: New York State has one of the strictest certification and approval processes in North America for laboratory tests.  Canadian medical authorities have done nothing but lie about, criticize and malign Igenex for many years based upon opinion not science, simply because Canadians were turning to Igenex for better testing. Igenex has helped thousands of sick Canadians get their life Continues →

Review of the National Institute for Health and Care Excellence in UK guidelines for Lyme disease

[CanLyme Note: NICE in the UK, similar to the Public Health Agency of Canada (PHAC) is given statutory distinction.  NICE published Lyme disease guidelines using their legislated privilege.  In Canada, the Association of Medical Microbiology and Infectious Diseases (AMMI) and PHAC have openly supported the NICE guidelines. PHAC regularly abuses its legislated privilege and AMMI continually makes misleading false statements to Continues →

Parenting When Children Have Lyme Disease: Fear, Frustration, Advocacy

Emilie M. Gaudet 1 , Odette N. Gould 1,*, Vett Lloyd 2 1 Department of Psychology, Mount Allison University, Sackville, NB E4L 1C7 Canada 2 Department of Biology, Mount Allison University, Sackville, NB E4L 1G7 Canada * Author to whom correspondence should be addressed. Healthcare 2019, 7(3), 95; doi.org/10.3390/healthcare7030095 Abstract Increasing numbers of Canadians, including children and adolescents, are being infected with Borrelia burgdorferi and contracting Lyme disease. Continues →

A Case of Tularemia in a Prosthetic Joint Infection

https://doi.org/10.3928/01477447-20190627-01 Abstract Periprosthetic infections occur in approximately 0.8% to 1.9% of all total knee arthroplasties (TKAs). Even with these low rates, it is rare to find a zoonotic bacterium causing a periprosthetic infection. In this case report, the authors identify the second documented case of a total joint infection with Francisella tularensis in the world and the first in the United States. Continues →

The new draft of the Infectious Disease Society of America (IDSA) guidelines open for public comment for 45 days.

The IDSA has presented their draft guidelines which with a brief scan appear not much different then their old controversial poorly evidenced guidelines.  Much of the same old players and 3 token patients. Typical unequal representation. Public comments close August 10th. Take your time, make notes before you enter their controlled comment format process as you have to submit all Continues →

Metamorphoses of Lyme disease spirochetes: phenomenon of Borrelia persisters

Parasites & Vectors 2019 12:237 Natalie Rudenko; Maryna Golovchenko; Katerina Kybicova and Marie Vancova Published May 16, 2019 Abstract The survival of spirochetes from the Borrelia burgdorferi (sensu lato) complex in a hostile environment is achieved by the regulation of differential gene expression in response to changes in temperature, salts, nutrient content, acidity fluctuation, multiple host or vector dependent factors, and leads to the formation of dormant subpopulations of Continues →

Microbiome analysis of Ixodes scapularis ticks from New York and Connecticut.

Ahead of print abstract…April 15, 2019 Abstract We employed high throughput sequencing to survey the microbiomes of Ixodes scapularis collected in New York and Connecticut. We examined 197 individual I. scapularis adults and pools from 132 adults and 197 nymphs. We detected Borrelia burgdorferi sensu stricto in 56.3% of individual ticks, Anaplasma phagocytophilum in 10.6%, Borrelia miyamotoi in 5%, Babesia Continues →

Three-antibiotic cocktail clears ‘persister’ Lyme bacteria in mouse study

April 23rd, 2019 A new study from researchers at the Johns Hopkins Bloomberg School of Public Health found that a slow-growing variant form of Lyme bacteria caused severe symptoms in a mouse model. The slow-growing variant form of Lyme bacteria, according to the researchers, may account for the persistent symptoms seen in ten to twenty percent of Lyme patients that Continues →

Tick-borne pathogen detection in midgut and salivary glands of adult Ixodes ricinus

Lejal et al. Parasites Vectors (2019) 12:152 https://doi.org/10.1186/s13071-019-3418-7 Abstract Background: The tick midgut and salivary glands represent the primary organs for pathogen acquisition and trans‑ mission, respectively. Specifcally, the midgut is the frst organ to have contact with pathogens during the blood meal uptake, while salivary glands along with their secretions play a crucial role in pathogen transmission to the Continues →

Bartonella henselae Bloodstream Infection in a Boy With Pediatric Acute-Onset Neuropsychiatric Syndrome

[CanLyme Note: Bartonella bacteria can be transmitted by ticks, cat scratches, dog saliva, etc.] Published in the Jounral of Central Nervous System Disease, March 18th, Edward B Breitshwerdt et al Abstract Background: With the advent of more sensitive culture and molecular diagnostic testing modalities, Bartonella spp. infections have been documented in blood and/or cerebrospinal fluid specimens from patients with diverse neurological symptoms. Pediatric Continues →

Presence of Babesia odocoilei and Borrelia burgdorferi Sensu Stricto in a Tick and Dual Parasitism of Amblyomma inornatum and Ixodes scapularis on a Bird in Canada

John D. Scott, Kerry L. Clark  and Lance A. Durden  published 20 March 2019 Abstract: Wild birds transport ticks into Canada that harbor a diversity of zoonotic pathogens. However, medical practitioners often question how these zoonotic pathogens are present in their locality. In this study, we provide the first report of an Amblyomma inornatum tick cofeeding with a blacklegged tick, Continues →

Systemic Sarcoidosis Associated with Exposure to Borrelia burgdorferi in a 21-Year-Old Man

ABSTRACT Objective: Here we describe a rare case of systemic sarcoidosis in a healthy young man with neuroborreliosis as a putative trigger. Case: A 21-year-old forestry worker was diagnosed with systemic sarcoidosis involving his lungs, kidneys and skin. Additional diagnostics revealed signs indicative of a recent infection with Borrelia burgdorferi. The patient was treated successfully with prednisolone and antibiotics. Conclusion: Sarcoidosis is a multisystem Continues →

Study of pediatric patients shows two-tier testing results cannot rule out Lyme borreliosis.

Two-Tier Lyme Disease Serology Test Results Can Vary According to the Specific First-Tier Test Used Published: February 22, 2019 Abstract Background Variability in 2-tier Lyme disease test results according to the specific first-tier enzyme immunoassay (EIA) in children has not been examined rigorously. In this study, we compared paired results of clinical 2-tier Lyme disease tests to those of the Continues →