Medical Publications & Research

Canadian Lyme treatment guidelines have changed dramatically in the past few years. CanLyme is dedicated to promoting accurate and up-to-date medical information.

The article abstracts below have primarily been sourced from: PubMed.gov or the specific journal in which they were published. Please click the PubMed or journal link to read the whole article on their site.

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Recent in: Medical Publications

Motivations and Experiences of Canadians Seeking Treatment for Lyme Disease Outside of the Conventional Canadian Health-Care System

Abstract   Objective: We aimed to describe the experiences of Canadians who seek diagnosis and treatment for Lyme disease outside of the conventional Canadian health-care system. Methods: Forty-five individuals who had sought treatment for Lyme disease outside of the conventional Canadian health-care system were recruited from Lyme support and advocacy groups across Canada to answer open-ended questions about their experiences. Continues →

A 4-year-old boy with ataxia and aphasia

[CanLyme Note: The rashes shown in this case are dismissed Canada-wide by doctors who are not taught about multiple rashes, and the worst of it is that if you are not in a “known endemic area” Lyme disease will be dismissed. In reality, Lyme disease occurs anywhere in Canada where our songbirds birds fly. If you have robins, finches and wrens Continues →

Chronic Lyme disease – does it exist?

“Her symptoms started quickly: neck pain, extreme fatigue and intermittent fever and chills. The woman had been healthy until then, and since she enjoyed gardening and landscaping at her rural Maryland home, she wondered if a tick bite might have given her Lyme disease although she had not noticed the telltale bull’s-eye skin lesion. Her doctor told her it was Continues →

WSU researchers crack the Lyme disease code

The next time a tick feeds on you, Washington State University researchers hope to make sure persistent arthritis caused by Lyme disease doesn’t linger for a lifetime. Troy Bankhead, associate professor in WSU’s Veterinary Microbiology and Pathology department, and his team have spent more than a decade analyzing an immune evasive protein of Borrelia burgdorferi, the bacterium that causes tick-borne Continues →

Lyme Disease: Diversity of Borrelia Species in California and Mexico Detected Using a Novel Immunoblot Assay

Abstract Background: With more than 300,000 new cases reported each year in the United States of America (USA), Lyme disease is a major public health concern. Borrelia burgdorferi sensu stricto (Bbss) is considered the primary agent of Lyme disease in North America. However, multiple genetically diverse Borrelia species encompassing the Borrelia burgdorferi sensu lato (Bbsl) complex and the Relapsing Fever Borrelia (RFB) group are capable of causing tickborne Continues →

Lyme Disease Frontiers: Reconciling Borrelia Biology and Clinical Conundrums

Abstract Lyme disease is a complex tick-borne zoonosis that poses an escalating public health threat in several parts of the world, despite sophisticated healthcare infrastructure and decades of effort to address the problem. Concepts like the true burden of the illness, from incidence rates to longstanding consequences of infection, and optimal case management, also remain shrouded in controversy. At the Continues →

Potential treatment for Lyme disease kills bacteria that may cause lingering symptoms, study finds

March 12, 2020 “For decades, the routine treatment for Lyme disease has been standard antibiotics, which usually kill off the infection. But for up to 20% of people with the tick-borne illness, the antibiotics don’t work, and lingering symptoms of muscle pain, fatigue and cognitive impairment can continue for years — sometimes indefinitely. A new Stanford Medicine study …” Read Continues →

The General Symptom Questionnaire-30 (GSQ-30): A Brief Measure of Multi-System Symptom Burden in Lyme Disease

[CanLyme Note: The term post-treatment Lyme disease syndrome (PTLDS) referenced in this article is contentious as it implies treatment has eradicated the infectious Lyme disease borrelia bacteria. There is an abundance of evidence showing that the bacteria can survive recommended treatment periods. Many people do well with longer term treatment while others do not respond at all. Other limitations of Continues →

Disulfiram (Tetraethylthiuram Disulfide) in the Treatment of Lyme Disease and Babesiosis: Report of Experience in Three Cases

Abstract   Three patients, each of whom had required intensive open-ended antimicrobial therapy for control of the symptoms of chronic relapsing neurological Lyme disease and relapsing babesiosis, were able to discontinue treatment and remain clinically well for periods of observation of 6–23 months following the completion of a finite course of treatment solely with disulfiram. One patient relapsed at six Continues →

Most recent American Psychiatric Association guidelines… check for Lyme disease in evaluation.

[CanLyme Note: The wording indicates locally endemic infectious diseases so that would also include the known co-infections of Lyme and other vector-borne diseases.  We need to find out what the Canadian Psychiatric Association (CPA) guidelines are relative to infectious diseases.  CanLyme has asked the CPA for their position on this. Limiting their investigation to the current anti-body testing model may miss Continues →

Repurposing disulfiram (Tetraethylthiuram Disulfide) as a potential drug candidate against Borrelia burgdorferi in vitro and in vivo

This article is a preprint and has not been certified by peer review – Posted Nov 15th, 2019 ABSTRACT Lyme disease caused by the Borrelia burgdorferi (Bb or B. burgdorferi) is a most common vector-borne, multi-systemic disease in USA. Although, most Lyme disease patients can be cured with a course of antibiotic treatment, a significant percent of patient population fail to be Continues →

Scotland, UK: Killer tick-borne parasite imitating malaria-like diseases is discovered by scientists in the UK

November 2019 by Shreyas Tanna Medical Herald A tick-borne parasite which causes a deadly malaria-like illness is spreading in the UK. Deadly malaria-like diseases are being spread in the UK by a tick-borne parasite. Babesia venatorum, the name of the discovered parasite, lives in sheep in the Scottish Highlands, according to researchers. People visiting the region have been warned by Continues →

Extensive Distribution of the Lyme Disease Bacterium, Borrelia burgdorferi Sensu Lato, in Multiple Tick Species Parasitizing Avian and Mammalian Hosts across Canada

Abstract Lyme disease, caused by the spirochetal bacterium, Borrelia burgdorferi sensu lato (Bbsl), is typically transmitted by hard-bodied ticks (Acari: Ixodidae). Whenever this tick-borne zoonosis is mentioned in medical clinics and emergency rooms, it sparks a firestorm of controversy. Denial often sets in, and healthcare practitioners dismiss the fact that this pathogenic spirochetosis is present in their area. For distribution of Bbsl Continues →

Rickettsial infections of the central nervous system

[CanLyme Note: The Canadian medical community is absolutely under-informed on tick-borne disease. Medical leadership in Canada, managed by non-medical (PHAC), medically unethical (AMMI), scientifically unethical (CIHR), taxpayer funded gatekeepers for the for-profit medical industry insure never ending sickness that generates billions of dollars while denying access to policy making decisions of those most affected… patients and their experts. When will there Continues →