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“Lyme disease affects children more than any other age group, but the young ones are often difficult to diagnose, especially before they’ve developed the vocabulary to describe how they’re feeling. To help parents recognize symptoms and prevent serious illness, I chatted with Charlotte Mao, MD, a pediatric infectious disease physician who trained at Harvard Medical School…
Tick species are undergoing range expansions across Canada due to global warming, animal migration, and land fragmentation. It is estimated that their range is expanding northwards by 35–55km per year. Species posing the greatest risk to humans are the Ixodes scapularis (blacklegged tick) and the Ixodes pacificus (Western blacklegged tick). The risk of human tick-borne infections is increasing. Populations…
“Spiroplasma spp. are intracellular organisms that belong to the class Mollicutes, which include Mycoplasma spp. These bacteria have a single-layer cell membrane, cannot be visualized by Gram staining, require special substrates for growth, and can be diagnosed by genetic methods (6). Plants, insects, and ticks are known reservoirs (7). S. ixodetis was initially reported in…
Healthy Debate Response 22-07-14 “‘Medical gaslighting’ harming long-COVID patients, Fong A, Healthy Debate 22-07-13: https://healthydebate.ca/2022/07/topic/medical-gaslighting-long-covid/ “Pandemics disable people — the history lesson that policymakers ignore” -Spinney L, 2022 Thank you for the article. The golden era of discovery in medicine is over. Physicians are no longer looking for root causes of diseases. Medicine is being…
“A 21-day-old girl presented to the emergency department of an Ontario children’s hospital in early summer with a 1-day history of rash on the left arm and 3 days of decreased activity, poor feeding (not waking to feed, decreased volumes) and abdominal distension. She had no fever, weight loss, irritability, recent travel or known infectious…
Sound Sensitivity (Hyperacusis) and the Lyme Disease Connection (Increased sensitivity to certain frequency and volume ranges of sound) Carbamazepine in the Treatment of Lyme Disease–Induced Hyperacusis https://neuro.psychiatryonline.org/…/10.1176/jnp.11.1.97 AETIOLOGY AND CLINICAL PRESENTATIONS OF AUDITORY PROCESSING DISORDERS—A REVIEW HTTP://ADC.BMJ.COM/CONTENT/85/5/361.SHORT TINNITUS, HEARING LOSS, SOUND SENSITIVITY AND THE LYME DISEASE CONNECTION Otolaryngologic aspects of Lyme disease. https://www.ncbi.nlm.nih.gov/pubmed/2041438 Central Auditory Processing Disorder https://link.springer.com/…/10.1007%2F978-0-387-79948-3… Lyme…
Abstract Serological diagnosis of Lyme disease suffers from considerable limitations. Yet, the technique cannot currently be replaced by direct detection methods, such as bacterial culture or molecular analysis, due to their inadequate sensitivity. The low bacterial burden in vasculature and lack of consensus around blood-based isolation of the causative pathogen, Borrelia burgdorferi, are central to this…
March 7, 2022 Abstract Assay sensitivity can be a limiting factor in the use of PCR as a tool for the detection of tick-borne pathogens in blood. We evaluated the performance of Tick-borne disease Capture Sequencing Assay (TBDCapSeq), a capture sequencing assay targeting tick-borne agents, to test 158 whole blood specimens obtained from the Lyme…
ABSTRACT Lyme disease is a tick-borne infection caused by the bacteria Borrelia burgdorferi. Current diagnosis of early Lyme disease relies heavily on clinical criteria, including the presence of an erythema migrans rash. The sensitivity of current gold- standard diagnostic tests relies upon antibody formation, which is typically delayed and thus of limited utility in early…
Abstract By using commercial insurance claims data, we estimated that Lyme disease was diagnosed and treated in ≈476,000 patients in the United States annually during 2010–2018. Our results underscore the need for accurate diagnosis and improved prevention. Lyme disease is caused by Borrelia burgdorferi spirochetes, which are transmitted to humans by certain Ixodes spp. ticks (1). The infection can…
[Canlyme Note: The Lyme disease guidelines of the IDSA, AAN, and ACR are simply a further example of their continued assault on scientific peer reviewed evidence. Science is ignored and their intentional misinformation becomes intrenched, causing untold harm to millions of sufferers globally including pregnant women and fetuses. Canadian infectious disease physician, William R Bowie continues…
October 29th, 2021 Victoria P Sanderson 1, Iain L Mainprize 1, Lisette Verzijlenberg 1, Cezar M Khursigara 2, Melanie K B Wills 1 Abstract Serological diagnosis of Lyme disease suffers from considerable limitations. Yet, the technique cannot currently be replaced by direct detection methods, such as bacterial culture or molecular analysis, due to their inadequate sensitivity. The low bacterial burden in vasculature and lack…
Abstract The bacterial pathogen responsible for causing Lyme disease, Borrelia burgdorferi, is an atypical Gram-negative spirochete that is transmitted to humans via the bite of an infected Ixodes tick. In diderms, peptidoglycan (PG) is sandwiched between the inner and outer membrane of the cell envelope. In many other Gram-negative bacteria, PG is bound by protein(s),…
A retrospective study of 270 post-treatment Lyme patients identified the most debilitating neurological symptoms, paving the way for future studies on root causes of disease and better treatments. The largest study to-date characterizing ongoing symptoms [1] of Lyme patients after antibiotic treatment has been published by a group of investigators at Harvard-affiliated hospitals and Invisible International, a non-profit organization….
Abstract Lyme disease, often characterized as a readily treatable infection, can be a debilitating and expensive illness, especially when patients remain symptomatic following therapy for early disease. Identifying and promoting highly effective therapeutic interventions for US patients with erythema migrans (EM) rashes that return them to their pre-infection health status should be a priority. The…
