Category Archives: Medical Publications

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Detection of Lyme Disease Bacterium, Borrelia burgdorferi sensu lato, in Blacklegged Ticks Collected in the Grand River Valley, Ontario, Canada

Scott et al. Received: 2016.09.29; Accepted: 2016.12.28; Published: 2017.02.08 Abstract We document the presence of blacklegged ticks, Ixodes scapularis, in the Grand River valley, Centre Wellington, Ontario. Overall, 15 (36%) of 42 I. scapularis adults collected from 41 mammalian hosts (dogs, cats, humans) were positive for the Lyme disease bacterium, Borrelia burgdorferi sensu lato (s.l.). Using real-time PCR testing and Continues →

Global Network on Institutional Discrimination: Lyme disease patients denied care and insurance coverage because of missing diagnostic codes

News provided by Global Network on Institutional Discrimination Feb 08, 2017, 10:04 ET VERO BEACH, Fla., Feb. 8, 2017 /PRNewswire-USNewswire/ — Struck by a duck? Burned because your water skis caught on fire? Have a bizarre personal appearance? Fortunately, the World Health Organization has assigned over 68,000 diagnostic codes to cover these and thousands of other conditions. When your doctor Continues →

Draft of report to parliament regarding Bill 442 now online and open to public input.

February 7th, 2017 As per the requirements of Bill 442, An Act respecting a Federal Framework on Lyme Disease Health Canada held a conference on Lyme disease in May of 2016.  It was a well balanced conference that revealed significant divergent opinions among experts on the most important issues to the affected Canadian… diagnosis and treatment. Without engaging the stakeholders for input, Continues →

A technology backed by Bill Gates may revolutionize diagnostics for Lyme disease

Diana Pryor, CNBC news associate   February 7th, 2017 While the medical and health community is putting a spotlight on diseases like Zika, Ebola and tuberculosis, another disease, transmitted by ticks, is getting little notice: Lyme disease. The ticks that carry Lyme disease are spreading rapidly across the U.S. and are now located in nearly half of the country. The CDC Continues →

MicroRNA and mRNA Transcriptome Profiling in Primary Human Astrocytes Infected with Borrelia burgdorferi.

Abstract   Lyme disease is caused by infection with the bacterium Borrelia burgdorferi (Bb), which is transmitted to humans by deer ticks. The infection manifests usually as a rash and minor systemic symptoms; however, the bacteria can spread to other tissues, causing joint pain, carditis, and neurological symptoms. Lyme neuroborreliosis presents itself in several ways, such as Bell’s palsy, meningitis, Continues →

First report of a blacklegged tick, Ixodes scapularis Say (Acari: Ixodidae), parasitizing a raptor in Canada

Systematic & Applied Acarology 22(2): 208–216 (2017) http://doi.org/10.11158/saa.22.2.5 Abstract We document the first report of a blacklegged tick, Ixodes scapularis Say, parasitizing an American Kestrel, Falco sparverius Linnaeus (Falconiformes: Falconidae), in Canada. A fully engorged I. scapularis nymph was collected from the base of the tongue of an American Kestrel nestling recovered at Mirabel, Québec. This nestling had recently fledged Continues →

Antibiotic gel shows promise in preventing onset of Lyme borreliosis following tick bite

December 2016 Topical azithromycin for the prevention of Lyme borreliosis: a randomised, placebo-controlled, phase 3 efficacy trial   An antibiotic gel based on azithromycin, helps with prevention of Lyme disease following a tick bite. That is the finding of a multi-centre international study, in which MedUni Vienna’s Department of Clinical Pharmacology played an important part. The study is now been Continues →

The Lyme disease pathogen Borrelia burgdorferi infects murine bone and induces trabecular bone loss

Tian Tian Tang, Lucia Zhang, Anil Bansal, Marc Grynpas, and Tara J. Moriarty Accepted Manuscript Posted Online 12 December 2016 Infect. Immun. doi:10.1128/IAI.00781-16 Copyright © 2016 Tang et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license. ABSTRACT Lyme disease is caused by members of the Borrelia burgdorferi sensu lato species Continues →

Woman’s Mystery Illness Turns Out to Be Tick-Borne Disease

By Gillian Mohney and Dr. Sabrina Anna Rebis A 66-year-old woman’s mysterious illness that left her feverish and with slurred speech initially stumped her doctors. As the woman’s condition continued to deteriorate, an infectious disease doctor eventually identified the cause — the woman had contracted a bacterial disease caused by a tick bite. Researchers from George Washington University School of Medicine Continues →

Commercial test kits for detection of Lyme borreliosis: a meta-analysis of test accuracy

November 2016 Abstract: The clinical diagnosis of Lyme borreliosis can be supported by various test methodologies; test kits are available from many manufacturers. Literature searches were carried out to identify studies that reported characteristics of the test kits. Of 50 searched studies, 18 were included where the tests were commercially available and samples were proven to be positive using serology Continues →

Ceftriaxone Pulse Dosing Fails to Eradicate Biofilm-Like Microcolony B. burgdorferi Persisters Which Are Sterilized by Daptomycin/ Doxycycline/Cefuroxime without Pulse Dosing

Published Nov 2016 Abstract   Although the majority of Lyme disease patients can be cured, at least 10–20% of the patients continue to suffer from persisting symptoms such as fatigue, muscular and joint pain, and neurologic impairment after standard 2–4 week antibiotic treatment. While the causes for this post-treatment Lyme disease symptoms are unclear, one possibility is due to Borrelia Continues →

Established Population of Blacklegged Ticks with High Infection Prevalence for the Lyme Disease Bacterium, Borrelia burgdorferi Sensu Lato, on Corkscrew Island, Kenora District, Ontario

2016; 13(11): 881-891. doi: 10.7150/ijms.16922 Abstract We document an established population of blacklegged ticks, Ixodes scapularis, on Corkscrew Island, Kenora District, Ontario, Canada. Primers of the outer surface protein A (OspA) gene, the flagellin (fla) gene, and the flagellin B (flaB) gene were used in the PCR assays to detect Borrelia burgdorferi sensu lato (s.l.), the Lyme disease bacterium. In Continues →

Dr. Nevena Zubcevik of the Harvard Medical School dispels some long held, over published myths about Lyme disease

Dispelling myths … “Dr. Nevena Zubcevik of the Harvard Medical School, and co-director of the Dean Center for Tick-Borne Illnesses, warned that the medical community is not keeping up with current findings. For example, “The conception that the tick has to be attached for 48 hours is completely outdated,” she said, citing studies that show ticks can transmit disease in Continues →