Category Archives: Medical Publications

Recent in: Medical Publications

Antibiotic gel shows promise in preventing onset of Lyme borreliosis following tick bite

December 2016 Topical azithromycin for the prevention of Lyme borreliosis: a randomised, placebo-controlled, phase 3 efficacy trial   An antibiotic gel based on azithromycin, helps with prevention of Lyme disease following a tick bite. That is the finding of a multi-centre international study, in which MedUni Vienna’s Department of Clinical Pharmacology played an important part. The study is now been Continues →

The Lyme disease pathogen Borrelia burgdorferi infects murine bone and induces trabecular bone loss

Tian Tian Tang, Lucia Zhang, Anil Bansal, Marc Grynpas, and Tara J. Moriarty Accepted Manuscript Posted Online 12 December 2016 Infect. Immun. doi:10.1128/IAI.00781-16 Copyright © 2016 Tang et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license. ABSTRACT Lyme disease is caused by members of the Borrelia burgdorferi sensu lato species Continues →

Woman’s Mystery Illness Turns Out to Be Tick-Borne Disease

By Gillian Mohney and Dr. Sabrina Anna Rebis A 66-year-old woman’s mysterious illness that left her feverish and with slurred speech initially stumped her doctors. As the woman’s condition continued to deteriorate, an infectious disease doctor eventually identified the cause — the woman had contracted a bacterial disease caused by a tick bite. Researchers from George Washington University School of Medicine Continues →

Commercial test kits for detection of Lyme borreliosis: a meta-analysis of test accuracy

November 2016 Abstract: The clinical diagnosis of Lyme borreliosis can be supported by various test methodologies; test kits are available from many manufacturers. Literature searches were carried out to identify studies that reported characteristics of the test kits. Of 50 searched studies, 18 were included where the tests were commercially available and samples were proven to be positive using serology Continues →

Ceftriaxone Pulse Dosing Fails to Eradicate Biofilm-Like Microcolony B. burgdorferi Persisters Which Are Sterilized by Daptomycin/ Doxycycline/Cefuroxime without Pulse Dosing

Published Nov 2016 Abstract   Although the majority of Lyme disease patients can be cured, at least 10–20% of the patients continue to suffer from persisting symptoms such as fatigue, muscular and joint pain, and neurologic impairment after standard 2–4 week antibiotic treatment. While the causes for this post-treatment Lyme disease symptoms are unclear, one possibility is due to Borrelia Continues →

Established Population of Blacklegged Ticks with High Infection Prevalence for the Lyme Disease Bacterium, Borrelia burgdorferi Sensu Lato, on Corkscrew Island, Kenora District, Ontario

2016; 13(11): 881-891. doi: 10.7150/ijms.16922 Abstract We document an established population of blacklegged ticks, Ixodes scapularis, on Corkscrew Island, Kenora District, Ontario, Canada. Primers of the outer surface protein A (OspA) gene, the flagellin (fla) gene, and the flagellin B (flaB) gene were used in the PCR assays to detect Borrelia burgdorferi sensu lato (s.l.), the Lyme disease bacterium. In Continues →

Dr. Nevena Zubcevik of the Harvard Medical School dispels some long held, over published myths about Lyme disease

Dispelling myths … “Dr. Nevena Zubcevik of the Harvard Medical School, and co-director of the Dean Center for Tick-Borne Illnesses, warned that the medical community is not keeping up with current findings. For example, “The conception that the tick has to be attached for 48 hours is completely outdated,” she said, citing studies that show ticks can transmit disease in Continues →

Steroid Use Questioned for Common Lyme Disease Manifestation

[CanLyme Note: Facial palsy, Bell’s Palsy, is not as common in Lyme patients as reported. It is easily recognized making those patients much more likely to be diagnosed. Most patients with Lyme disease do not experience facial palsy as it is typically a facial numbness and tingling/burning, often around the mouth, nose, and the tongue.] Sept. 7th, 2016 Compared to antibiotic Continues →

CanLyme director responds to Canadian Medical Association Journal article

Response to Doctors Gregson and Quach Robert G. Murray, DDS, Director, CanLyme Re: “The Lyme law” Zubek, 187:520-521doi:10.1503/cmaj.115-0029 The problem with Lyme disease in Canada will only continue to grow to the point where the numbers affected will simply overwhelm the idea that Lyme Borreliosis (LB) is hard to catch and easy to treat with a short round of antibiotics. Continues →

First Record of Ixodes affinis Tick (Acari: Ixodidae) Infected with Borrelia burgdorferi Sensu Lato Collected from a Migratory Songbird in Canada

Scott, et al.  Published June 30th, 2016 Abstract Migratory songbirds transport hard-bodied ticks (Acari: Ixodidae) into Canada during northward spring migration, and some of these bird-feeding ticks harbor a wide diversity of pathogenic microorganisms. In this study, we collected a nymphal Ixodes affinis Neumann from a Common Yellowthroat, Geothylypis trichas (Linnaeus), at Ste-Anne-de-Bellevue, Québec, and it was infected with the Continues →

Fox5 TV New York – LYME AND REASON: THE CAUSE AND CONSEQUENCE OF LYME DISEASE

June 30th, 2016 “LYME AND REASON: THE CAUSE AND CONSEQUENCE OF LYME DISEASE” presents an in-depth look at the cause and effect of Lyme disease, including the controversy over testing, the issues of misdiagnosis, and the personal struggles of medical professionals and patients contending with this life-changing illness. -Brian A. Fallon, MD, MPH, Director of the Center for Neuroinflammatory of Continues →

If Not Lyme Disease, What Caused This Man’s Fever?

June 16, 2016 by Lisa Sanders, M.D. THE PRESENTING PROBLEM A doctor thought he knew what brought on this patient’s flulike symptoms, but antibiotics weren’t helping. “Nonno says he doesn’t feel good,” the 8-year-old girl reported, handing her mother a digital thermometer. The woman looked at the readout — just under 102 degrees. Her father, the child’s grandfather, had been Continues →

Australia: Murdoch University researchers found new bacteria in Australian ticks removed from echidnas

June 15, 2016 MURDOCH University researchers have detected a new species of bacteria in echidna-biting Australian ticks. The recent discovery was published by Dr Charlotte Oskam, from Murdoch University’s Vector and Water-borne Pathogen Research Group (VWBPRG), in the parasitology journalParasites and Vectors. To date, little has been documented about microorganisms harboured within Australian native ticks or their potential to transmit Continues →