Types of Antibiotics

Top 4 types of antibiotics

There are many types of antibiotics; but, according to Deutsche Borreliose-Gesellschaft’s “Diagnosis and Treatment of Lyme borreliosis Guidelines”, only a few have proved effective against the bacteria that cause Lyme disease. These antibiotics are:

  1. Tetracyclines and gycylcyclines
  2. Macrolides
  3. Betalactams
  4. Nitroimidazoles

Unsuitable antibiotics

The following antibiotics are not suitable for treating Lyme disease, but are sometimes prescribed by doctors without adequate Lyme knowledge.

  • Carboxypenicillins
  • Acylaminopenicillins (supposedly effective; no clinical experience; usually employed in the treatment of inpatients)
  • First generation cephalosporins (cefazolin, cefotoxitin)
  • Oral first and second generation cephalosporins, except for cefuroxime axetil
  • Quinolones
  • Aminoglycosides
  • Chloramphenicol
  • Clindamycin
  • Glycopeptide antibiotics
  • Folate antagonists (except for trimethoprim according to Gasser(51))
  • Cotrimoxazole
  • Atovaquone
  • Nitrofurans
  • Erythromycin

Learn more about antibiotic treatment by downloading Deutsche Borreliose-Gesellschaft’s “Diagnosis and Treatment of Lyme borreliosis Guidelines”.

Download treatment guidelines